Autologous Chondrocyte Transplantation: validation of the therapy protocol for Joint Cartilage Lesions

Hospital Israelita Albert Einstein0 个研究点开始时间: 2019年6月5日最近更新: 2023年5月29日

适应症

试验速览

暂无简介。

•Male; age between 18 and 40 years; with or without anterior cruciate ligament (ACL) injury; lesion of the articular cartilage in the femur or patella; degrees 2 or 3 of the International Cartilage Repair Society (ICRS) classification; diameter greater than 2 cm; symptomatic; without improvement with conservative treatment based on physical therapy, weight loss and medications

•Superficial chondral lesion (classification ICRS grade 1); Subchondral bone lesion (ICRS grade 4); Osteoarthritis (Kellgren-Lawrence rating greater than 1); Misalignment of the mechanical axis of the lower limb in the frontal plane; Multiple ligament lesions; Previous surgeries in the affected knee; Meniscal lesions not sutured; Systemic inflammatory diseases; Inability to adhere to the rehabilitation protocol; Functional limitations due to pain in the spine or hips; Claustrophobia; Metal implants that ensure the performance of magnetic resonance; Obesity (BMI greater than 30); Smoking; Gestation; Cognitive changes with inability to read, understand and sign the EHIC.

发起方