Skip to main content
MedPathMedPath Home
Clinical Trials/ISRCTN48911177
ISRCTN48911177
Completed
Not Applicable

Autologous Chondrocyte Transplantation/Implantation Versus Existing treatments: a randomised controlled trial

Keele University (UK)0 sites400 target enrollmentMay 18, 2001
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Not specified
Sponsor
Keele University (UK)
Enrollment
400
Status
Completed
Last Updated
9 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
May 18, 2001
End Date
TBD
Last Updated
9 years ago
Study Type
Interventional

Investigators

Sponsor
Keele University (UK)

Eligibility Criteria

Inclusion Criteria

  • •Current inclusion criteria as of 09/11/2012:
  • •1\. Symptomatic chondral defect(s) on the medical or lateral femoral condyle, trochlea or patella suitable for either ACT or one of the existing conventional treatments (debridement, abrasion, drilling, microfracture, mosaicplasty)
  • •2\. Surgical treatment for the same defect carried out at least 12 months previously, that has not relieved symptoms
  • •3\. Not more than two defects, not kissing and total area not greater than 12cm2
  • •4\. Likely to comply with appropriate physiotherapy
  • •Previous inclusion criteria until 09/11/2012:
  • •1\. Symptomatic chondral defect(s) on the medical or lateral femoral condyle or trochlea suitable for either ACT or one of the existing conventional treatments (debridement, abrasion, drilling, microfracture, mosaicplasty)
  • •2\. Surgical treatment for the same defect carried out at least 12 months previously, that has not relieved symptoms
  • •3\. Not more than two defects, not kissing and total area not greater than 12cm2
  • •4\. Likely to comply with appropriate physiotherapy

Exclusion Criteria

  • •1\. Concurrent meniscectomy/osteotomy or untreated malalignment of patella
  • •2\. Generalised osteoarthritis, inflammatory condition or history of mesenchymal tumors
  • •3\. Patient in different clinical trial involving the knee, currently or in last 6 months

Outcomes

Primary Outcomes

Not specified

Similar Trials

Recruiting
Not Applicable
Own Cartilage Cells Transplantation: validation of the therapy protocol for Cartilage LesionsArticular pain/kneeC05.550.114.606.500A02.165.407C05.550.091
RBR-6fgy76Hospital Israelita Albert Einstein
Completed
Not Applicable
Autologous chondrocyte implantation (ACI) in the treatment of early Osteoarthritis (OA)Musculoskeletal Diseases: Osteoarthritis (OA)Musculoskeletal DiseasesOsteoarthritis (OA)
ISRCTN54356626Record Provided by the NHSTCT Register - 2006 Update - Department of Health80
Unknown
Phase 1
Study to treat patients with knee defects using adult stem cellsHealth Condition 1: null- Focal chondral defects in the knee
CTRI/2015/02/005568Aware Global Hospitals100
Completed
Phase 1
Autologous Chondrocyte Transplantation For Articular Cartilage RegenerationTear; Knee, Cartilage, Articular
NCT01503970Instituto Nacional de Rehabilitacion10
Unknown
Phase 1
Repair and Regeneration of Knee cartilage
CTRI/2015/06/005841Sri Sathya Sai Institute of Higher Learning1