Comparison of autogenous tooth substitute graft and xenogeneic bone graft materials used for osseous defects after surgical removal of impacted lower third molars: Split-mouth randomized clinical trial

Phase 1

• Conditions: The study conducts in healthy volunteers who have either deep mesioangulation or horizontal impacted teeth which will cause loss of alveolar bone support after surgical removal of the teeth. The bone graft materials will be put inside the tooth sockets in order to prevent the loss of alveolar bone support as aforementioned.; Autogenous tooth substitute graft; Xenogeneic bone graft; Impacted teeth; Alveolar bone loss; Alveolar preservation

• Registration Number: TCTR20221216003
• Lead Sponsor: Mahidol University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-12-16
• Study Completion: 2023-09-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Enrolling by invitation
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

1.Male or female aged between 20-30 years old
2.Bilateral mesioangulated or horizontal impacted mandibular 3rd molars with present 2nd molars
3.No pathological lesion involved with both the mandibular 2nd and 3rd molars and surrounding bones
4.Co-operative and able to follow the instructions

Exclusion Criteria

1.Patients with systemic disease or medical conditions that may impair the wound healing process
2.Patients with existing active infection at either site of mandibular 3rd molars
3.Patients with generalized periodontal disease
4.Patients with smoking habit
5.Patients with orthodontic appliance

Study & Design

• Study Type: Interventional
• Study Design: Not specified