MedPath

European Quality Improvement Programme for Acute Coronary Syndromes

Not Applicable
Conditions
Acute Coronary Syndrome
Interventions
Behavioral: Quality Improvement Programme
Registration Number
NCT00716430
Lead Sponsor
Royal Brompton & Harefield NHS Foundation Trust
Brief Summary

The main hypothesis to be tested is that the use of a quality improvement programme will lead to measurable improvements in the management of care and use of evidence based treatments for patients presenting to hospital with non-ST elevation acute coronary syndromes.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
3500
Inclusion Criteria

Patients with a good clinical history of ACS and at least one of the following:

  • New or transient ST or T wave changes on the ECG consistent with acute myocardial ischaemia
  • Elevation of troponin or other cardiac markers to levels indicative of myocardial necrosis according to local laboratory values
Exclusion Criteria
  • Evidence of persistent ST elevation on the ECG
  • Use of early reperfusion therapy
  • Patients >80 years
  • Patients transferred from another hospital

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
QIQuality Improvement ProgrammeQuality Improvement Centres
Primary Outcome Measures
NameTimeMethod
Composite of 7 outcome measures to assess aggregate potential for improvement in care using the QI programme:1:risk stratification within 24 hrs, 2:early coronary angiography, 3:anticoagulation, 4:beta-blockers, 5:statins, 6:ACE-inhibitors, 7:Clopidogrel10 months
Secondary Outcome Measures
NameTimeMethod
Clinical outcomes at discharge including death and myocardial infarction10 months
Estimated costs of care for patients10 months
Estimated costs and economic evaluation of potential cost-effectiveness of QI programme10 months

Trial Locations

Locations (37)

Szpital Zachodni

🇵🇱

Grodzisk Mazowiecki, Poland

Szpital w Grojcu

🇵🇱

Grojec, Poland

Centre Hospitalier de Chambery

🇫🇷

Chambery, France

Centre Hospitalier d'Ussel

🇫🇷

Ussel, France

Centre Hospitalier de Riom Guy Thomas

🇫🇷

Riom, France

Hopitaux Drome Nord de Romans-sur-Isere

🇫🇷

Romans-sur-Isere, France

Hospital Universitario Joan XXIII

🇪🇸

Tarragona, Spain

Ospedale Generale Provinciale di Macerata

🇮🇹

Macerata, Italy

Cardiology dept. B, CHU Hopital G. Montpied

🇫🇷

Clermont Ferrand, France

Ospedale Civile di Mirano

🇮🇹

Mirano, Italy

Centre Hospitalier de la region d'Annecy

🇫🇷

Annecy, France

Szpital we Wloclawku

🇵🇱

Wloclawek, Poland

Ospedale Morgagni-Pierantoni

🇮🇹

Forli, Italy

CHU de Grenoble

🇫🇷

Grenoble, France

Szpital w Plocku

🇵🇱

Plock, Poland

Szpital w Siedlcach

🇵🇱

Siedlce, Poland

Barnet General Hospital

🇬🇧

Barnet, United Kingdom

Yeovil District Hospital

🇬🇧

Yeovil, United Kingdom

Centre Hospitalier Pierre Bazin

🇫🇷

Voiron, France

Ospedale M. Bufalini

🇮🇹

Cesena, Italy

Szpital w Ciechanowie

🇵🇱

Ciechanow, Poland

Ospedale di Livorno

🇮🇹

Livorno, Italy

Radomski Szpital Specjalistyczny

🇵🇱

Radom, Poland

Szpital Specjalistyczny SPZOZ w Radom

🇵🇱

Radom, Poland

SP CSK- Medical University of Warsaw

🇵🇱

Warsaw, Poland

Swietofrzyskie Centrum Chorob Serca

🇵🇱

Kielce, Poland

Hospital Universitario Germans Trias

🇪🇸

Badalona, Spain

Hospital del Mar

🇪🇸

Barcelona, Spain

Hospital Universitario Vall d'Hebron

🇪🇸

Barcelona, Spain

Hospital Josep Trueta

🇪🇸

Girona, Spain

Basildon Hospital

🇬🇧

Essex, United Kingdom

Hospital de Tortosa Virgen de la Cinta

🇪🇸

Tortosa, Spain

Hospital de Terrassa

🇪🇸

Terrassa-Barcelona, Spain

Antrim Area Hospital

🇬🇧

Antrim, United Kingdom

Warwick Hospital

🇬🇧

Warwick, United Kingdom

Royal Albert Edward Infirmary

🇬🇧

Wigan, United Kingdom

York District Hospital

🇬🇧

York, United Kingdom

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