Establishment of Tongue Image Database and Machine Learning Model for Malignant Tumors Diagnosis

Completed

• Conditions: Malignant Tumor
• Interventions: Other: Tongue images, coating on the tongue and clinical data of patients with malignant tumors and healthy people will be collected.

• Registration Number: NCT04793672
• Lead Sponsor: Zhejiang Cancer Hospital

Brief Summary

The tongue images of malignant tumors and corresponding healthy people will be collected to establish the tongue image database. Deep learning will be carried out by computer and artificial intelligence to construct the early screening, diagnosis, prognosis and prognosis model of various malignant tumors based on tongue image for the diagnosis and treatment of malignant tumors.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-05-01
• Study First Submitted: 2021-03-05
• Study First Submitted QC: 2021-03-09
• Study First Posted: 2021-03-11
• Primary Completion: 2022-04-01
• Study Completion: 2023-12-01
• Status Verified: 2024-07
• Last Update Submitted: 2024-07-27
• Last Update Posted: 2024-07-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 4100

Inclusion Criteria

• 18≤age≤80
• Histologically or cytologically confirmed malignant tumor
• No prior chemotherapy, radiotherapy, biotherapy, immunotherapy or other anti-tumor treatment for malignant tumor
• Subject volunteers to join the study, Signs informed consent, has good compliance and can cooperate with follow-up

Exclusion Criteria

• Two or more kinds of malignant tumors at the same time
• Malignant tumor that has been treated by chemotherapy, radiotherapy, biotherapy, immunotherapy or other anti-tumor therapy
• Subjects who had other factors that might force them to terminate the research ahead of time, such as the development of other severe disease (including mental disease) that required combined treatment, seriously abnormal laboratory examination value, and family or social factors that might affect the subject safety or experimental data collection, as judged by the researchers

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients with malignant tumors and healthy people	Tongue images, coating on the tongue and clinical data of patients with malignant tumors and healthy people will be collected.	Tongue images, coating on the tongue and clinical data of patients with malignant tumors and healthy people will be collected.

Primary Outcome Measures

Name	Time	Method
The differences of tongue images between patients with malignant tumors and healthy people.	1 year
Overall Survival (OS)	3 years

Secondary Outcome Measures

Name	Time	Method
Disease free survival（DFS）	1 year

Trial Locations

Locations (2)

Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital); 🇨🇳 Hangzhou, Zhejiang, China

Zhejiang Cancer Hospital; 🇨🇳 Hangzhou, Zhejiang, China