CTRI/2023/01/049280
Not yet recruiting
Phase 2
A Prospective Interventional randomized study to assess efficacy of Angiotensin Receptor Nephrilysin Inhibitor (Sacubitril/Valsartan) in right ventricular systolic dysfunction with normal LV functionâ??
MDM hospitalDr SN Medical College0 sites0 target enrollmentTBD
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- MDM hospitalDr SN Medical College
- Status
- Not yet recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients of Right Ventricular systolic dysfunction with Normal Left ventricular systolic function as diagnosed by transthoracic echocardiography parameters such as TAPSE( \<16mm), PAsP( \>25mm Hg), tricuspid annular velocity( \<10 cm/sec), Fractional area change( \<35%) and blood markers such as NT\-proBNp( \>400pg/ml).
Exclusion Criteria
- •1\.Patients with LVEF \<50%
- •2\.Pregnancy
- •3\. Severe hepatic impairment (Child. Pugh C)
- •4\.Severe renal imapairment (eGFR \<30 ml/min/1\.73m2\)
- •Hypersensitivity to any component of the product
- •A prior history of angioedema due to an ACEI or ARB
Outcomes
Primary Outcomes
Not specified
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