Hemodynamic Measurements at Different Inclinations of the Head
Not Applicable
- Conditions
- Hypovolemic Shock
- Interventions
- Other: 0.9% saline solution
- Registration Number
- NCT02046785
- Lead Sponsor
- Federal University of Uberlandia
- Brief Summary
The purpose of this study is to determine whether hemodynamic measures vary in angles bedside before and after volume challenge.
- Detailed Description
* Check if values of central venous pressure (CVP), pulse pressure variation (Δpp), heart rate (HR), mean arterial pressure ((PAM) vary in different angles headboards
* Compare values of CVP, Δpp, HR and MAP as predictors of blood volume after supply of 500 ml of 0.9% saline solution.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
- Being in circulatory shock and have at least one of the following criteria to identify loss of tissue perfusion: systolic blood pressure <90 mmHg or need for vasoactive drugs, urine output below 0.5 ml / kg / h.
- Being under sedation, assessed by the scale of Richmond agitation and sedation (RASS) -5, mechanically ventilated in volume control mode with tidal volume between 8 to 12 ml/kg, PEEP to 8 cm H2O.
- Tue signing the informed consent by legal guardian.
Exclusion Criteria
- Presence cardiac arrhythmias.
- Presence of abdominal or thoracic trauma.
- Contraindication for passive elevation of the members.
- Hypoxia significant PaO2/FiO2 < or equal 100.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description 0.9% saline solution 0.9% saline solution comparing values obtained before and after administration of 500 ml of 0.9% saline
- Primary Outcome Measures
Name Time Method Different Backrest position's effect on CVP, CO and ∆PP measures Data collection was performed at admission or within 10 days of hospitalization between September 2013 and February 2014.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Intensive Care Unit, Clinical Hospital, Federal University of Uberlandia
🇧🇷Uberlandia, Minas Gerais, Brazil