Measurements of Exhaled Nitric Oxide in Healthy Subjects in Thailand

Completed

Brief Summary: The purpose of this study is to determine fractional exhaled nitric oxide (FeNO) level in healthy subjects among Thai populations.

Detailed Description: Fractional exhaled nitric oxide (FeNO) were produced from epithelial cells of inflammatory airways and eosinophils and this gas was discovered since 1991.

Fractional exhaled nitric oxide (FeNO) has direct association with severity of inflammation of bronchial trees and sputum eosinophils and use for additional investigation for diagnosis asthma or inflammatory airway diseases.

There are many factors from previous studies that associate with level of fractional exhaled nitric oxide (FeNO), one of that factors is race therefore we can't use level from another studies with different race for use as reference and there is no study about level of fractional exhaled nitric oxide in Thai population.

It is therefore desirable to examine level of fractional exhaled nitric oxide (FeNO) in healthy subjects among Thai population and will be the main objective of this research.

Recruitment & Eligibility

Inclusion Criteria

Exclusion Criteria

smoker or past history of smoking
asthma, allergic rhinitis, chronic respiratory disease or other chronic illness
history of wheezing within 12 months before enrollment
history of upper or lower respiratory tract infection within 6 weeks before enrollment
drink ethanol within 48 hours before enrollment
drink caffeine within day before enrollment
during pregnancy
chronic use of any drugs
participate other project within 30 days

Primary Outcome Measures

Name	Time	Method
fractional exhaled nitric oxide level	10 minutes (average time ), on the day of enrollment

Secondary Outcome Measures

Name	Time	Method

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