Measurements of Exhaled Nitric Oxide in Healthy Subjects in Thailand
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- fractional exhaled nitric oxide level
研究概览
简要总结
The purpose of this study is to determine fractional exhaled nitric oxide (FeNO) level in healthy subjects among Thai populations.
详细描述
Fractional exhaled nitric oxide (FeNO) were produced from epithelial cells of inflammatory airways and eosinophils and this gas was discovered since 1991.
Fractional exhaled nitric oxide (FeNO) has direct association with severity of inflammation of bronchial trees and sputum eosinophils and use for additional investigation for diagnosis asthma or inflammatory airway diseases.
There are many factors from previous studies that associate with level of fractional exhaled nitric oxide (FeNO), one of that factors is race therefore we can't use level from another studies with different race for use as reference and there is no study about level of fractional exhaled nitric oxide in Thai population.
It is therefore desirable to examine level of fractional exhaled nitric oxide (FeNO) in healthy subjects among Thai population and will be the main objective of this research.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 6 Years 至 60 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy subjects in community
排除标准
- •smoker or past history of smoking
- •asthma, allergic rhinitis, chronic respiratory disease or other chronic illness
- •history of wheezing within 12 months before enrollment
- •history of upper or lower respiratory tract infection within 6 weeks before enrollment
- •drink ethanol within 48 hours before enrollment
- •drink caffeine within day before enrollment
- •during pregnancy
- •chronic use of any drugs
- •participate other project within 30 days
结局指标
主要结局
fractional exhaled nitric oxide level
时间窗: 10 minutes (average time ), on the day of enrollment
次要结局
未报告次要终点
研究者
Nualanong Visitsunthorn
Professor
Mahidol University