The Effect of the Selected Anaesthesia Method on Morbidity and Mortality in Frail Patients Scheduled for Transurethral Surgery
概览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
- 入组人数
- 180
- 主要终点
- Postoperative morbidity
概览
简要总结
The aim of this study is to comparatively evaluate the effects of different anaesthesia methods (spinal anaesthesia and general anaesthesia) administered to frail elderly patients scheduled for transurethral surgery (e.g. TUR-Prostate or TUR-Bladder) on postoperative morbidity and mortality rates.
详细描述
When planning transurethral surgery in frail patients, optimising the anaesthesia method is critical in minimising perioperative risks. In a 2021 study by Darwish et al. (1), 28,486 TUR-P cases were grouped according to the selected anaesthesia method. The 30-day mortality rate was 0.4% in the neuroaxial anaesthesia (spinal/epidural) group and 0.7% in the general anaesthesia group; the neuroaxial anaesthesia group showed significantly better outcomes in terms of secondary morbidity rates such as mortality and sepsis. However, there are studies in the literature supporting general anaesthesia. A study by Ayoub et al. (4) emphasised that in frail patients, similar morbidity rates can be achieved with general anaesthesia or spinal anaesthesia; spinal anaesthesia may increase the risk of hypotension and bradycardia. Based on these studies, the selection of the appropriate anaesthesia method for transurethral procedures is of critical importance in terms of patient morbidity and mortality rates. This study aims to contribute to clinical guidelines by clarifying which type of anaesthesia is safer in this specific demographic and clinical group. Within the scope of the research, parameters such as complications associated with the anaesthesia method, length of hospital stay, readmission rate, and 30-day mortality are analysed with the aim of determining the most appropriate and safest anaesthesia method for the vulnerable patient group.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —(Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Elderly patients aged 65 and over
- •ASA (American Society of Anaesthesiologists) physical condition classification I-III patients
- •meeting the criteria for frailty
排除标准
- •Non-elective emergency surgeries
- •Patients under 65 years of age
- •Patients classified as ASA Class IV
- •Patients unable to provide informed consent due to cognitive impairment
- •Patients who have previously undergone major neurological or cardiac surgery
结局指标
主要结局
Postoperative morbidity
时间窗: 30-day postoperative morbidity
Morbidity rates up to the 30th day postoperatively will be recorded. Patients will be contacted by phone and the data will be recorded.
Postoperative mortality
时间窗: 30-day postoperative mortality
Mortality rates up to the 30th day postoperatively will be recorded. Patients will be contacted by phone and the data will be recorded.
次要结局
- Duration of surgery(Until the end of the surgery)
- Length of hospital stay(first week after surgery)
- intraoperative complications,(perioperative period)