Effect of Anesthesia Techniques on Quality of Recovery Scores in HOLEP Surgery

Not yet recruiting

• Conditions: HoLEP; Anesthesia; Combine Spinal and Epidural; QoR-40; Anesthesia, General; Anesthesia,Spinal

• Registration Number: NCT07020390
• Lead Sponsor: TC Erciyes University

Brief Summary

The aim of this observational study is to evaluate the effects of different anesthesia techniques on the quality of recovery (QoR) and patient satisfaction in male patients, typically older adults with benign prostatic hyperplasia, undergoing Holmium Laser Enucleation of the Prostate (HoLEP).

Participants will undergo HoLEP surgery under one of three anesthesia techniques-general, spinal, or combined spinal-epidural anesthesia-and will complete the QoR-40 questionnaire both before and after the surgery.

Detailed Description

These patients will be informed about the preoperative study and the Quality of Recovery 40 (QoR-40) scoring scale will be applied by the responsible researcher preoperatively and within 24 hours postoperatively, and the values will be recorded. The anesthesia method of the patients will be determined as determined routinely according to the patient's age, additional diseases, duration of surgery, and patient preference and will be applied by an experienced anesthesiologist. Routine intraoperative follow-ups of all patients will be performed. Surgeries completed without any complications will be taken to the recovery unit at the end of the procedure, and stable patients will be transferred to the ward. In patients whose ward follow-ups continue routinely, catheter-related bladder discomfort will be evaluated within 24 hours postoperatively, postoperative patient and surgeon satisfaction will be evaluated according to the 5-point Likert scale, and the QoR-40 score will be recorded. Postoperative pain levels and analgesic needs will be recorded. Parameters will be compared by dividing into groups according to the anesthesia method.

Study Timeline

• Status Verified: 2025-06
• Study First Submitted: 2025-06-03
• Study First Submitted QC: 2025-06-11
• Last Update Submitted: 2025-06-11
• Study First Posted: 2025-06-13
• Last Update Posted: 2025-06-13
• Study Start: 2025-06-20
• Primary Completion: 2026-03-15
• Study Completion: 2026-06-15

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: Male
• Target Recruitment: 450

Inclusion Criteria

• Patients scheduled for HOLEP surgery due to benign prostatic hyperplasia.
• Patients who consent to participate in the study.

Exclusion Criteria

• Refusal to participate in the study
• Presence of cognitive impairment
• Use of psychoactive medications
• Failure of the intraoperative anesthesia technique and necessity to change the anesthesia method
• Requirement for reoperation or admission to the intensive care unit
• Voluntary withdrawal from the study

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The Quality of Recovery Score (QoR-40)	Baseline (preoperative) and postoperative day 1	The QoR-40 is a self-rated questionnaire that consists of 40 items to evaluate the pain levels and physical and emotional state of patients, comprising five subscales: emotional state (n = 9), physical comfort (n = 12), patient support (n = 7), physical independence (n = 5), and pain (n = 7). Each item is scored on a five-point Likert scale ranging from 1 to 5. The scores for the subscales are given by the sum of the corresponding items, and the total score is computed by a summation of all items. The total score ranges from 40 to 200. Higher scores indicate higher levels of functioning or well-being.; Change in QoR-40 score from preoperative to postoperative day 1 to evaluate overall recovery quality.

Secondary Outcome Measures

Name	Time	Method
Patient satisfaction and surgeon satisfaction	Postoperative day 1	Patient and surgeon satisfaction was rated using a 5-option Likert scale at postoperative day 1: 1 = very bad, 2 = bad, 3 = moderate, 4 = good and 5 = excellent.

Trial Locations

Locations (1)

Erciyes University; 🇹🇷 Melikgazi, Kayseri, Turkey

Erciyes University

🇹🇷Melikgazi, Kayseri, Turkey

Gamze Talih

Contact

+905447604780

gamzetalih@gmail.com