The Effect of Low-İntensity Combined Exercises on Fatigue, Balance and Quality of Life in Patients With Early Stage ALS
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Amyotrophic Lateral Sclerosis
- Sponsor
- Istanbul University - Cerrahpasa (IUC)
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- The fatigue severity scale (FSS)
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
The aim of this study is to investigate the effects of low-intensity combined exercises on balance, fatigue and quality of life applied to patients with ALS.
Detailed Description
Balance problems and signs of fatigue are seen in early-stage ALS patients. While balance problems lead to falls in ALS patients, fatigue also affects a part of their lives. Studies investigating the effects of low-intensity exercise on fatigue, balance, and quality of life in patients with early-stage ALS are rare. This study will investigate the effects of low-intensity combined exercises on balance, fatigue and quality of life in patients with ALS. Participants will be randomly divided into Supervised and Home groups. Low-intensity exercises will be applied to the home exercise group as a home program for 1 hour a day, 3 days a week, for 6 weeks. Low-intensity exercises will be applied to the supervised exercise group for 1 hour a day, 3 days a week for 6 weeks, accompanied by a physiotherapist. Evaluations will be made at the beginning and at the end of the treatment. Berg Balance Scale, Fatigue Severity Scale (FSS), Amyotrophic Lateral Sclerosis Assessment Questionnaire-40 (ALSAQ-40) and revised Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R) will be used to evaluate patients before and 6 weeks after treatment.
Investigators
Xhennet Muriqi
Researcher
Istanbul University - Cerrahpasa (IUC)
Eligibility Criteria
Inclusion Criteria
- •Being diagnosed with early-stage ALS by a neurologist
- •Disease duration in the range of 1-18 months
- •ALSFRS-R score \> 24 higher
- •Without infectious disease
- •Saturation \>95
- •Heart rate \<92
Exclusion Criteria
- •History of other neurological disease
- •Inability to walk
- •With mechanical ventilation
- •People with Heart and Respiratory Insufficiency
- •People with neuropsychological or cognitive impairment
- •Dyspnea after ALS
Outcomes
Primary Outcomes
The fatigue severity scale (FSS)
Time Frame: Post-intervention (7th week)
FSS is a self-report scale of nine items examining motivation, physical function, responsibilities, work, family or social life, exercise, fatigue, frequency of problems, and priority of symptoms.
Secondary Outcomes
- Berg Balance Scale (BBS)(Post-intervention (7th week))
- Amyotrophic Lateral Sclerosis Assessment Questionnaire (ALSAQ-40)(Post-intervention (7th week))
- ALS Functional Rating Scale Revised (ALSFRS-R)(Post-intervention (7th week))