The influence of oxytocin on alcohol craving in social drinkers during exposure to alcohol related cues
Not Applicable
- Conditions
- F10.2
- Registration Number
- DRKS00009253
- Lead Sponsor
- Zentralinstitut für Seelische GesundheitKlinik für Abhängiges Verhalten und Suchtmedizin
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 17
Inclusion Criteria
Age: Between 18 and 65 years
- male gender
- Fully Informed Consent
- ability to take part in a fMRI
- Written Informed Consent
- Minimum 2 drinking days per week
Exclusion Criteria
- No fully Informed Consent
- No written Informed Consent
- Female gender
- Age under 18 years ord over 65 years
- psyciatric disorders of axis I (according to DSM IV or ICD 10 except for nicotine dependence.
- Severe iinternal and neurological comorbities
- medication with interacts with oxytocin
- current drug abuse/dependence except for nicotine
- alcoholization at the measuring days
-contraindications for fMRI
.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary end point:<br><br>Differences in the functional brain activity between the oxytocin and the placebo condition during confrontation with alcohol associated cues
- Secondary Outcome Measures
Name Time Method Secunary end point:<br><br>Differences in subjective craving between the oxytocin and the placebo condition during confrontation with alcohol associated cues (as measured with a visual analoge scale)