Exercise With Dual Task in Knee Osteoarthritis

Not Applicable

Completed

• Conditions: Knee Osteoarthritis
• Interventions: Other: Resistance exercise

• Registration Number: NCT05280080
• Lead Sponsor: University of Valencia

Brief Summary

The purpose of this study is to evaluate the neuromuscular and perceptual responses, pain intensity and performance in patients with severe knee osteoarthritis in a preoperative setting with low-load resistance training with a self-regulated mathematical dual-task.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-02-15
• Study First Submitted QC: 2022-03-05
• Study First Posted: 2022-03-15
• Study Start: 2022-03-21
• Status Verified: 2022-05
• Primary Completion: 2022-05-13
• Study Completion: 2022-05-20
• Last Update Submitted: 2022-05-23
• Last Update Posted: 2022-05-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• men and women above 55 years old.
• diagnosed with severe knee osteoarthritis.
• scheduled for unilateral TKA surgery in a local hospital during 2021- 2022.

Exclusion Criteria

• pain in the contralateral limb (maximum pain, ≥80 of 100 mm on a VAS during daily activities).
• another hip or knee joint replacement in the previous year.
• any medical condition in which exercise was contraindicated.
• participated in exercise programs (>2 days/week, training at intensities of 10-15RM) in the 6 months prior to the study.
• history of stroke, brain surgery, major depression, or any self-perceived cognitive alterations that could affect the performance of dual tasks.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Dual Task	Resistance exercise	Knee extensions while also doing a self-regulated mathematical dual-task.
Regular Task	Resistance exercise	Knee extensions.

Primary Outcome Measures

Name	Time	Method
Self-reported pain intensity (Visual Analogue Scale (VAS) Scale 0-10)	Pre exercise, immediate post session, and 10 minutes after session.	Change from baseline to the end of the session, and the change between the dual-task and the regular condition.
Performance	During each experimental session and during each exercise condition.	Maximum number of exercise repetitions performed.
Pressure pain thresholds	Pre exercise, immediate post session, and 10 minutes after session.	Change from baseline to the end of the session, and the change between the dual-task and the regular condition.
HDsEMG	During each experimental session and during each exercise condition.	Change from baseline to the end of the session, and the change between the dual-task and the regular condition.

Secondary Outcome Measures

Name	Time	Method
Pain Catastrophizing Scale (PCS)	Pre session.	People are asked to indicate the degree to which they have certain thoughts and feelings when they are experiencing pain using the 0 (not at all) to 4 (all the time) scale. A total score is yielded (ranging from 0-52), along with three subscale scores assessing rumination, magnification and helplessness, with higher scores reflecting worse condition.
Perceived difficulty of the dual-task.	Immediate post exercise.	Based on an 11-point numerical rating scale.
Tampa Scale of Kinesiophobia (TSK 11)	Pre session.	Its score range is 11-44, with higher scores reflecting worse condition.
Chronic Pain Self-Efficacy Scale (CPSS)	Pre session.	The Chronic Pain Self-Efficacy Scale (CPSS) is designed to measure chronic pain patients' perceived self-efficacy to cope with the consequences of chronic pain. The CPSS measures three domains of pain self-efficacy: pain management, physical functioning, and coping with symptoms. A total score is yielded (ranging from 220-2200), with higher scores reflecting a better condition.
WOMAC questionaire for patients with hip or knee osteoarthritis.	Pre session.	The WOMAC is a disease-specific self-administered questionnaire for patients with hip or knee osteoarthritis. It has a multidimensional scale made up of 24 items grouped into three dimensions: pain (5 items), stiffness (2 items) and physical function (17 items). For each item, it uses a Likert scale with five response levels, representing different degrees of intensity (none, mild, moderate, severe or extreme) that are scored from 0 to 4. The final score for the WOMAC is determined by adding the aggregate scores for pain, stiffness and function. The higher the score, the worse the patient's condition.
Heart Rate	Pre exercise, immediate post session, and 10 minutes after session.	Change from baseline to the end of the session, and the change between the dual-task and the regular condition.

Trial Locations

Locations (1)

Clinic Universitary Hospital of Valencia; 🇪🇸 Valencia, Spain