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Clinical Trials/NL-OMON40066
NL-OMON40066
Completed
Not Applicable

Gene Expression and Genome Wide Association Study on remission of asthma - Gene Expression and GWAS on remission of asthma

niversitair Medisch Centrum Groningen0 sites277 target enrollmentTBD
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Conditionsasthmahyperresponsivenes10006436

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
asthma
Sponsor
niversitair Medisch Centrum Groningen
Enrollment
277
Status
Completed
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Observational invasive

Investigators

Eligibility Criteria

Inclusion Criteria

  • •Roorda cohort and the DAG cohort (asthma)
  • •1\. Age 18 years or older
  • •2\. Previous diagnosis of asthma
  • •3\. Bronchial hyperresponsiveness in childhood (Roorda Cohort)
  • •4\. In clinical or complete remission of asthma (DAG cohort)
  • •NORM study (healthy)
  • •1\. Age 18 years or older
  • •2\. FEV1 pre bronchodilator \> 80% predicted
  • •3\. No bronchial hyperresponsiveness; PC20 metacholinebromide \>32 mg/ml
  • •4\. Never diagnosed with asthma

Exclusion Criteria

  • •For all cohorts
  • •1\. Presence of serious concomitant diseases (Cancer, Cardiovascular disorders)
  • •2\. Pregnancy
  • •Additional exclusion criterium for metacholine challenge testing:
  • •3\. FEV1 below 1\.2 L

Outcomes

Primary Outcomes

Not specified

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