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临床试验/NL-OMON40066
NL-OMON40066已完成不适用

Gene Expression and Genome Wide Association Study on remission of asthma - Gene Expression and GWAS on remission of asthma

niversitair Medisch Centrum Groningen0 个研究点目标入组 277 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
277

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 99(—)

入选标准

  • Roorda cohort and the DAG cohort (asthma)
  • 1. Age 18 years or older
  • 2. Previous diagnosis of asthma
  • 3. Bronchial hyperresponsiveness in childhood (Roorda Cohort)
  • 4. In clinical or complete remission of asthma (DAG cohort)
  • NORM study (healthy)
  • 1. Age 18 years or older
  • 2. FEV1 pre bronchodilator > 80% predicted
  • 3. No bronchial hyperresponsiveness; PC20 metacholinebromide >32 mg/ml
  • 4. Never diagnosed with asthma

排除标准

  • For all cohorts
  • 1. Presence of serious concomitant diseases (Cancer, Cardiovascular disorders)
  • 2. Pregnancy
  • Additional exclusion criterium for metacholine challenge testing:
  • 3. FEV1 below 1.2 L

研究者

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