18F-FDG PET-MRI in patients with uterine cervical cancer - PETRA-C
Completed
- Conditions
- uterine cervical cancer10038594
- Registration Number
- NL-OMON41355
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
Patients > 18 years
Inoperable cervical cancer, FIGO stage IIb or higher, based on the investigation under anaesthesia
Treatment plan: (chemo) radiation with curative intent
Informed consent
Exclusion Criteria
Tumor relapse
Conisation or lymph node dissection in the past
Claustrophobia, pregnancy, fasting serum blood sugar >10mmol/l, morbid obesity, standard MRI contraindications and joint prosthesis (as possible cause of attenuation artefacts on PET-CT or PET-MRI)
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>1. Practical aspects of 18F-FDG PET-MRI protocol (e.g. imbedding of our current<br /><br>MRI protocol in the PET-MRI protocol, presence of artifacts, optimal patient<br /><br>preparation)<br /><br>2. Assessment of the primary tumor: size and FDG uptake on 18F-FDG PET-MRI<br /><br>versus 18F-FDG PET-CT)<br /><br>3. Lymph node visualisation on 18F-FDG PET-MRI versus 18F-FDG PET-CT (pelvic<br /><br>and paraaortal)<br /><br>4. Patient comfort during 18F-FDG PET-MRI versus 18F-FDG PET-CT<br /><br>5. Detection of distant metastases<br /><br>6. The possibilities of PET-MRI based radiation treatment planning in a PET-MRI<br /><br>system not specially equipped with radiotherapy treatment facilities will be<br /><br>explored.</p><br>
- Secondary Outcome Measures
Name Time Method <p>n.a.</p><br>