A study of the effects on oral bacteria with D-Tagatose chewing gum
Not Applicable
- Conditions
- Dental caries
- Registration Number
- JPRN-UMIN000026233
- Lead Sponsor
- Department of oral and maxillofacial surgery, Faculty of Medicine, Kagawa University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 24
Inclusion Criteria
Not provided
Exclusion Criteria
1) Low dental caries active person by saliva buffering ability test or intraoral examination 2) Person who cannot agree on participation of this exam even through parents or assistant 3) Antibiotics or anticancer drug, patient who was receiving the same treatment during radiation therapy treatment or within 1 year 4) Those judged unsuitable as subjects 5) Can not bite 3 g (2 tables) of gum for more than 10 minutes 6) Use of removable dentures, use of orthodontic treatment equipment 7) Salivary gland disease, xerostomia, renal dysfunction, abnormal liver function 8) Children under 6 years of age
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method About 10 ml of saliva is collected before starting the gum test and collected one week later periodically until the fourth week. Dilute saliva is seeded on BHI and Mitis Salivarious Bacitracin Agar (MSB) agar plates and bacterial counts are measured.
- Secondary Outcome Measures
Name Time Method Evaluate bacterial counts of Streptococcus mutans or Lactobacillus with Dentocult SM or Dentocult LB kit.