To compare Effectiveness of two drugs Esmolol and Lignocaine for decreasing the PressorResponse during artificial tube insertion in respiratory tube under General Anaesthesia.

Not yet recruiting

• Conditions: In this study we give drugs in healthy individuals which comes in Operation Theatre for laproscopic surgies to attenuate the hemodynamic responses of Direct Laryngoscopy and Endotracheal Intubation.

• Registration Number: CTRI/2023/06/054104
• Lead Sponsor: Dr Shriphal Meena

Brief Summary

In this study we will compare effectiveness of intravenous Dexmedetomidine (0.5microgram/kg) and Esmolol (0.5mg/kg) for attenuating the hemodynamic responses to laryngoscopy and endotracheal intubation in adult patients undergoing laparoscopic surgeries under general anesthesia procedures.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-06-15
• Study Start: 2023-08-14

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• Patients belonging to American Society of Anaesthesiologist (ASA) physical status grade I and II.
• Patients willing to give written informed consent.
• Weighing 40 to 70 kg.

Exclusion Criteria

• Patients having history of convulsion and history of allergy to anaesthestic agents used in study.
• Patients with anticipated difficult intubation i.e Mallampati class 3 or more,restricted neck movement or restricted mouth opening.
• Pregnant patients and lactating mothers.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To determine the difference in changes in Heart rate from baseline to different time intervals in the two groups.	0,1,3,5,10 minutes after Intubation.

Secondary Outcome Measures

Name	Time	Method
To determine the difference in changes in Heamodynamic Responses (SBP, DBP, MAP) from baseline to different time intervals in the two groups.	0,1,3,5,10 minutes after Intubation.

Trial Locations

Locations (1)

SMS MEDICAL COLLEGE AND HOSPITAL; 🇮🇳 Jaipur, RAJASTHAN, India

SMS MEDICAL COLLEGE AND HOSPITAL

🇮🇳Jaipur, RAJASTHAN, India

Dr Shriphal Meena

Principal investigator

09928350391

dr.shriphal@gmail.com