Study of different vasopressors for hypotention after spinal anaesthesia in Lower Section Caesarean Section(LSCS)
- Conditions
- american society of anaesiology (ASA ) class 1 and class 2 parients who posted in operation theatre for lower section caeserian section under spinal anaesthesia
- Registration Number
- CTRI/2018/09/015750
- Lead Sponsor
- Government Medical Collage Surat
- Brief Summary
Hypotension following spinal anaesthesia in LSCS isone of the common complication, having an incidence of around 60-80%. With theavailable western country data these doses of vasopressor produces bradycardia and othercomplications. Aim of the present study to compare the efficacy of ephedrine andphenylephrine for the treatment of maternal hypotention in Indian population, having comparatively less gestational weight,for the treatment of maternal hypotension after anaesthesia and evaluate theside effects of drugs and new-born assessment by APGAR score & Neonatalheart rate.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Female
- Target Recruitment
- 100
1)ASA Grade 1 and 2 2)Age 18 to 30 years 3)Patients with valid consent (informed and written) 4)Full term parturients with Singleton pregnancy posted for emergency/elective caesarean section under spinal anesthesia.
1)ASA grade III/IV patient 2)Contraindications to regional anesthesia 3)Hypersensitivity to the study drugs 4)Parturients taking tricyclic antidepressants and MAO inhibitors, because phenylephrine is contraindicated in these cases 5)Parturients with hypertension (BP ≥160/90) (PIH/HTN), cardio-vascular diseases, hyperthyroidism, atherosclerosis, bronchial asthm.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method This study is designed to comparatively evaluate the effects of phenylephrine and ephedrine used in treatment of spinal anaesthesia induced hypotension in patients undergoing LSCS. Intra-operation i will monitor pulse, blood pressure and any complication at every 2 minutes after giving these medication whenever hyphenation develops.
- Secondary Outcome Measures
Name Time Method If these vasopressureS will be given before the delivery of baby, we will monitor newborn baby for vitals(pulse)and APGAR score with effects in mother. We will monitor pulse and APGAR score of every newborn just after delivery and then once after 5 minutes.Intra and post operation we will look for any side effects in mother.
Trial Locations
- Locations (1)
new civil hospital surat, gujarat
🇮🇳Surat, GUJARAT, India
new civil hospital surat, gujarat🇮🇳Surat, GUJARAT, Indiadhavalkumar c patelPrincipal investigator9898866862dcp991717@gmail.com