Exercise Following Autologous Peripheral Blood Stem Cell Transplantation

Phase 3

• Conditions: Hematological Disease
• Interventions: Other: Supervised exercise

• Registration Number: NCT00883961
• Lead Sponsor: Charite University, Berlin, Germany

Brief Summary

The study evaluates the effects of a supervised exercise program on the physical performance, the mood and the complications of therapy in patients undergoing a high-dose chemotherapy followed by an autologous peripheral blood stem cell transplantation.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2009-04-17
• Study First Submitted QC: 2009-04-17
• Study First Posted: 2009-04-20
• Status Verified: 2009-12
• Study Start: 2009-12
• Last Update Submitted: 2009-12-21
• Last Update Posted: 2009-12-23
• Primary Completion: 2011-04
• Study Completion: 2011-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Age 18-70
• Hematological disease
• Treatment with high-dose chemotherapy followed by autologous stem cell transplantation
• Understanding of written German

Exclusion Criteria

• Cardiorespiratory, metabolical, osteoarticular or immunological diseases which can be aggravated by exercise
• Pathological stress-ECG at admission

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Supervised exercise	Supervised exercise	-

Primary Outcome Measures

Name	Time	Method
VO2max	At recruitment and after 3 weeks

Secondary Outcome Measures

Name	Time	Method
Mood	At recruitment and after 3 weeks
Duration of aplasia	3 weeks
Complications during hospitalization	3 weeks
Need for transfusion of platelets and red blood cells	3 weeks

Trial Locations

Locations (1)

Section Sports Medicine, Charité Universitätsmedizin Berlin, Hindenburgdamm 30; 🇩🇪 Berlin, Germany