Impact of a Pharmaceutical Consultation at Hospital Discharge on Adherence to Anti-infective Treatment After Returning Home
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Infection
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
- Enrollment
- 174
- Locations
- 1
- Primary Endpoint
- The presence/absence of treatment non-adherence
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
The main objective of this study is to evaluate the impact of a pharmaceutical consultation at the time of hospital discharge on the adherence of patients ; non-adherence is determined by the following criteria:
As concerns prescribed anti-infectious treatments, at least one of the following 4 criteria is true:
- . the patient did not go and get his/her treatment at the pharmacy;
- . the number of treatment units dispensed by the pharmacy is < the number of treatment units prescribed;
- . the patient stopped taking a treatment before the recommended time, or continued taking a treatment after the recommended time;
- . the number of treatment units taken by the patient (self-declaration) is < or > to the number of units prescribed.
Detailed Description
The secondary objectives of this study are : A- To assess the percentage of patients who obtained their anti- infective pharmaceuticals B- To evaluate the ratio of the number of units of anti- infective drugs dispensed by the pharmacy over the number of units of anti- infective drugs prescribed C- To determine the ratio of the number of premature discontinuations of anti -infective treatments over the number of lines of anti -infective treatments prescribed D- Evaluate the ratio of the number of units actually taken by the patient (based on a self-declaration) over the number of units of anti- infective drugs prescribed E- To measure the comprehension concerning anti- infective treatments after returning home (based on a quiz) F- To determine the risk factors for non- adherence to anti- infective therapy based on the characteristics of the study population G- Assess patient satisfaction concerning a pharmaceutical consultation at hospital discharge (questionnaire) H- Assess the impact of a pharmaceutical consultation on primary non-adherence (criteria 1 and 2) and secondary non- adherence (criteria 3 and 4)
Investigators
Eligibility Criteria
Inclusion Criteria
- •The patient must have given his/her informed and signed consent
- •The patient must be insured or beneficiary of a health insurance plan
- •The patient is hospitalized in the Infectious and Tropical Diseases department of the Nîmes University Hospital, and is scheduled for hospital discharge with one or more pharmaceutical prescriptions for anti-infectious treatments
Exclusion Criteria
- •The patient is participating in another study
- •The patient is in an exclusion period determined by a previous study
- •The patient is under judicial protection
- •The patient refuses to sign the consent
- •It is impossible to correctly inform the patient
- •The patient resides in a care establishment, or has home medical/nursing service
- •The patient is suffering from chronic infection (\>4 weeks of treatment required)
- •The patient is suffering from handicapping deafness, dementia, or does not have a telephone
- •Intravenous, intramuscular or subcutaneous anti-infectious treatments are prescribed
- •Prescription of antiretroviral treatments
Outcomes
Primary Outcomes
The presence/absence of treatment non-adherence
Time Frame: 1 week after end of treatment (expected max of 4 weeks)
As concerns prescribed anti-infectious treatments, at least one of the following 4 criteria is true: 1. . the patient did not go and get his/her treatment at the pharmacy; 2. . the number of treatment units dispensed by the pharmacy is \< the number of treatment units prescribed; 3. . the patient stopped taking a treatment before the recommended time, or continued taking a treatment after the recommended time; 4. . the number of treatment units taken by the patient (self-declaration) is \< or \> to the number of units prescribed.
Secondary Outcomes
- Test for measuring overall compliance (MAQ)(Day 0 (hospital discharge))
- Satisfaction Questionnaire concerning pharmaceutical consultation(Day 0 (hospital discharge))
- Number of anti-infectious drug units dispensed by the pharmacy / number of anti-infections drug units prescribed(1 week after end of treatment (expected max of 4 weeks))
- Socio-demographic characteristics(Day 0 (hospital discharge))
- Number of premature discontinuations of anti-infective therapies / the prescribed number of anti-infective treatments(1 week after end of treatment (expected max of 4 weeks))
- Number of anti-infectious drug units taken by the patient (self-declaration) / number of anti-infections drug units prescribed(1 week after end of treatment (expected max of 4 weeks))
- Delivery of anti-infectious therapy by the pharmacy (yes/no)(1 week after end of treatment (expected max of 4 weeks))
- Quiz on anti-infective therapy comprehension(Day 0 (hospital discharge))