Evaluation of Combined Venous Excess Grading System And Lung Ultrasound Score To Assess Organ Congestion In Adult Patients in Sepsis
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- To investigate whether a combined modified lung ultrasound score (LUS)and Venous Excess Ultrasound (VExUS) protocol called VExLUS score in adult patients with sepsis can improve sensitivity and early identification of fluid overload.
研究概览
简要总结
Introduction: Sepsis and septic shock are one of the most common indications for intensive care unit admission. Fluid resuscitation is one of the cornerstones in management of such patients. However, overzealous fluid therapy leads to congestion and poor perfusion. Point of care ultrasound can be used for venous excess ultrasound and combined with lung ultrasound to look for fluid overload state and to guide fluid therapy.
Aim of Study: To assess utility of combined lung ultrasound and venous excess grading system in early identification of fluid overload state and organ congestion
Materials& methods: Patient admitted with septic shock in our intensive care unit will be assessed for fluid overload using point of care ultrasound focusing on lung ultrasound (LUS) and Venous Excess Ultrasound (VExUS) scores. Combined VExLUS score will be ascertained along with various biochemical parameters and its outcome will be measured in terms of early diagnosis of fluid overload and end organ damage.
Clinical Significance: Combined lung ultrasound and Venous Excess Ultrasound grading can be used to identify fluid overload and tissue congestion at an early stage including identification of end organ damage due to congestion leading to poor perfusion for better clinical outcome and prognosis of patient.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 90.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients with septic shock requiring Intensive Care Unit admission.
- •2.Sepsis and septic shock criteria met as per surviving sepsis campaign guidelines 2021.
排除标准
- •1.No consent to participate in study 2.Indication for ICU admission other than sepsis 3.Patients with previously known conditions that interfere with portal Doppler assessments, namely liver cirrhosis, or severe tricuspid regurgitation or structural heart disease.
结局指标
主要结局
To investigate whether a combined modified lung ultrasound score (LUS)and Venous Excess Ultrasound (VExUS) protocol called VExLUS score in adult patients with sepsis can improve sensitivity and early identification of fluid overload.
时间窗: 28 days
次要结局
- 1.To correlate VExLUS score with signs of intensive fluid administration(2.To correlate VExLUS score with duration of mechanical ventilation, length of ICU-stay and 28-day mortality)
研究者
Dr Safiya Sherrin M K
Dayanand Medical College and Hospital, Ludhiana