Change in Brain Metabolism and Cognitive Function by Aripiprazole

Not Applicable

Completed

• Conditions: Antipsychotics; Cognition; Brain Metabolism; Dopamine Receptor Occupancy

• Registration Number: NCT01562808
• Lead Sponsor: Seoul National University Hospital

Brief Summary

Dopamine receptor occupancy and brain metabolism were measured using positron emission tomography after the administration of aripiprazole. Working memory performance was also measured using N-back task.

The investigators explored the relationship between changes in brain metabolism and working memory performance.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-01
• Primary Completion: 2010-05
• Study Completion: 2012-01
• Status Verified: 2012-03
• Study First Submitted: 2012-03-22
• Study First Submitted QC: 2012-03-23
• Last Update Submitted: 2012-03-23
• Study First Posted: 2012-03-26
• Last Update Posted: 2012-03-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 15

Inclusion Criteria

• healthy volunteers
• right-handed

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Exclusion Criteria

• any significant abnormality on routine lab
• any psychiatric disease

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Reaction time of correct response in N-back task	48 hrs after the administration of aripiprazole

Trial Locations

Locations (1)

Seoul National University Hospital; 🇰🇷 Seoul, Korea, Republic of