Effect of Aerobic Exercise with Blood Flow Restriction on Post-exercise Hypotension in Young Adults: the Role of Histamine Receptors
- Conditions
- Prehypertension (elevated Blood Pressure) or Hypertension
- Registration Number
- NCT06629337
- Lead Sponsor
- California Baptist University
- Brief Summary
It was hypothesized that aerobic exercise with blood flow restriction (BFR) induced post exercise hypotension (PEH), and the reduction in blood pressure (BP) was due to peripheral vasodilation via the histamine receptors. Ten male participants participated in this study. The participants were randomly assigned to walk for 10 minutes at 6.4 k/m, 0% grade with or without BFR after taking histamine receptor blockade. Following exercise, BP was measured at 10 min interval for 60 minutes. Heart rate (HR), stroke volume (SV), cardiac output (CO), mean arterial pressure (MAP), and total peripheral resistance (TPR) were evaluated.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 10
- good health,
- nonsmokers
- those not taking medications that could affect cardiovascular function
- hypertension
- muscular skeletal disorder
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Post-exercise hypotension before and after the histamine blockade 10 min, 20 min, 30 min, 40 min, 50 min, and 60 min post exercise Blood pressure change during 60 min (10 min interval) after BFR exercise
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
California Baptist University
🇺🇸Riverside, California, United States