The Norepinephrine Transporter: A Novel Target for Imaging Brown Adipose Tissue

Early Phase 1

Completed

• Conditions: Brown Adipose Tissue
• Interventions: Radiation: PET imaging

• Registration Number: NCT02038595
• Lead Sponsor: Yale University

Brief Summary

This study seeks to assess a novel imaging technique to image brown adipose tissue utilizing the norepinephrine transporter.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-09
• Primary Completion: 2013-12
• Study Completion: 2013-12
• Study First Submitted: 2014-01-10
• Study First Submitted QC: 2014-01-14
• Study First Posted: 2014-01-16
• Status Verified: 2015-07
• Last Update Submitted: 2020-03-27
• Last Update Posted: 2020-03-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• age 18-30 yrs
• BMI < 24 kg/m2
• Caucasian

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Exclusion Criteria

• Current neuro-psychiatric illness
• substance abuse
• medical or neurological illnesses likely to affect physiology or anatomy, i.e., uncontrolled hypertension, cardiovascular disorders
• current pregnancy
• current breast feeding
• suicidal ideation or behavior
• use of medications which potentially affect NET binding within 2 weeks of the PET scans.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Healthy subjects	PET imaging	Healthy subjects (male, female)

Primary Outcome Measures

Name	Time	Method
detection of brown adipose tissue based on PET imaging	1 year

Trial Locations

Locations (1)

Yale University; 🇺🇸 New Haven, Connecticut, United States