NCT03041480已完成不适用
The Association Between Periodontal Status, Serum Lipid Levels and Lipoprotein Associated Lipophosphase A2(Lp-PLA2) in Chronic Periodontitis Subjects and Healthy Controls: A Case Control Study
Meenakshi Ammal Dental College and Hospital0 个研究点目标入组 75 人开始时间: 2015年2月2日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 75
- 主要终点
- Estimation of serum Lp-PLA2
研究概览
简要总结
To assess the association between periodontal parameters, serum lipid profile and Lp-PLA2 level in systemically healthy Chronic Periodontitis subjects and healthy controls.
详细描述
Seventy five participants were divided into 3 groups. The groups consisted of GROUP I- generalized severe chronic periodontitis, GROUP II- generalized moderate chronic periodontitis and GROUP III- systemically and periodontally healthy volunteers who served as control. The selected patients were then evaluated for periodontal parameters, lipid profile and Lp-PLA2.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Other
入排标准
- 年龄范围
- 35 Years 至 64 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Subjects with age ≥ 35 years.
- •Presence of at least 24 teeth, with Clinical attachment loss (CAL) ≥ 5mm in more than 30% of sites.
- •Subjects with age ≥ 35 years.
- •Presence of at least 24 teeth, with Clinical attachment loss (CAL) between 3-4 mm in more than 30% of sites.
- •Subjects with age ≥ 35 years.
- •Healthy and intact periodontium
排除标准
- •Presence of any systemic disease or conditions that could affect periodontal tissues.
- •History of periodontal treatment in past 6 months.
- •Smoking and alcoholism
- •Anomalies of blood and immune system
- •Systemic medication or antibiotic treatment for the previous 6 months.
- •Pregnant females.
结局指标
主要结局
Estimation of serum Lp-PLA2
时间窗: 9 months
Serum Lp-PLA2 was estimated in all the groups using ELISA
次要结局
- Estimation of serum lipid profile(9 months)
研究者
Dr.Jaideep Mahendra
Professor
Meenakshi Ammal Dental College and Hospital
相似试验
招募中
不适用
The effect of periodontal care on lipid profiles in type 2 diabetic patients.type 2 diabetes mellitusJPRN-UMIN000004775ational Hospital Organization, Okayama Medical Center70
已完成
不适用
Is There a Relationship Between Hyperlipidemia and Periodontitis?Hyperlipidemia, Periodontal DiseaseNCT02826720Marmara University160
已完成
不适用
IL-6, IL-17 and IL-35 Levels in the Gingival Crevicular Fluid of Patients With Periodontitis and Healthy ControlsPeriodontitisNCT05306860Istanbul University60
已完成
不适用
Relationship Analysis Between Periodontal Disease and Atherosclerosis in Japanese Medical Cooperation ServicesAtherosclerosisPeriodontal DiseaseNCT01866761Okayama University116
Unknown
不适用
The Impact Of Periodontal Disease Treatment On The General Health Status In Chronic Haemodialyzed PatientsChronic Kidney DiseasePeriodontal DiseaseNCT01785355Anemia Working Group Romania30