Cognitive self-therapy (CST) for patients with chronic-recurrent depression or anxiety
Completed
- Conditions
- Depression, anxiety disordersMental and Behavioural DisordersRecurrent depressive disorder
- Registration Number
- ISRCTN61381864
- Lead Sponsor
- niversity Medical Centre Groningen (UMCG) (Netherlands)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 151
Inclusion Criteria
1. DSM IV diagnosis of chronic and/or recurrent depression, dysthemic disorder or (generalised) anxiety disorder
2. Duration of symptoms more than 2 years
3. 18-65 years
Exclusion Criteria
1. Suicidal behaviour
2. Psychosis
3. Substance dependency
4. IQ <85
5. Lack of insight in personal vulnerability in social contacts or relationship
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Symptoms of anxiety and depression (SCL-90; BDI; ZBV)
- Secondary Outcome Measures
Name Time Method 1. Quality of life<br>2. Social functioning<br>3. WHO Qol<br>4. Euroqol
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What neurobiological mechanisms underlie CST efficacy in chronic-recurrent depression and anxiety disorders?
How does CST compare to SSRIs or CBT in long-term outcomes for treatment-resistant depression patients?
Are specific genetic biomarkers (e.g., SLC6A4 polymorphisms) predictive of CST response in anxiety disorders?
What adverse events are associated with CST implementation in patients with recurrent depressive disorder?
What combination therapies (e.g., CST + pharmacotherapy) show synergistic effects in managing comorbid depression and anxiety?