Correlation of Right Ventricular diastolic function assessment by echo with six minute walk distance in patients with significant pulmonary artery hypertension

At the outset, we will obtain necessary approvals, including IRC (Institutional Review Committee), IEC (Institutional Ethics Committee) approval, and registration with CTRI (Clinical Trials Registry - India). Our study will focus on patients aged between 18 and 65 years, with echo suggestive of Significant pulmonary artery hypertension (TR velocity > 3.4m/s) in Kasturba Hospital, Manipal. Before the study, we will approach these patients and provide a detailed explanation of the research. Upon their understanding and agreement, informed consent will be obtained. Demographic details, clinical, laboratory valves and treatment receiving will be collected using proforma. Standard echocardiographic parameters which are required for the study will be recorded. They are advised to undergo six minute walk distance as per the ATS guidelines, under the supervision of certified cardiac rehabilitation physiotherapist and Cardilogy DM resident. Following this, Correlation of 6 minute walk distance with various 2d echo parameters of RV function will be analysed. There will be no need for additional visits or follow-up in this study. When standard protocols are followed, complications are rare. As noted previously, the self-paced character of the test limits their occurrence. The most common adverse event reported in the literature is oxygen desaturation below

80% resulting in termination of the test. Other complications include fatigue and mild shortness of breath, however patient will be doing six minute walk at his own pace. if such complications occur, he or she will be asked to stop the walk, as the six minute distance was under the supervision of certified cardiac rehabilitation physiotherapist and Cardilogy DM resident. The six minute walk test is routinely done in OPD settings to know functional capacity of patient.