Comparison of left ventricular diastolic function between normotensive diabetics and non-diabetics with similar left ventricular mass index
概览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- KMC,MCHP MAHE,Manipal
- 入组人数
- 642
- 试验地点
- 1
- 主要终点
- Peak E velocity
概览
简要总结
After departmental presentation, IRC, IEC approval and CTRI registration will be done. Patients will be enrolled in the study according to the inclusion criteria. Study details will be explained to the subjects, PIS will be provided and written informed consent will be obtained. Details about clinical history, findings on physical examination, investigations including biochemical tests will be noted. Standard echocardiographic views will be recorded along with connected ECG. Echocardiographic parameters of diastolic function are noted. The researcher is just observing and documenting the findings from the case. For controls these tests are standard of care.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)(—)
- 性别
- All
入选标准
- •Case Diabetic patients who are on curative lifestyle modification or antidiabetic medication Individuals who are not hypertensives Controls Non diabetic patients with same LV mass as case group.
排除标准
- •Genetically triggered causes of LV hypertrophy Metabolic storage disorders Valvular heart diseases producing LV obstruction Preexisting systolic dysfunction.
结局指标
主要结局
Peak E velocity
时间窗: At the time of recruitment
Peak A velocity
时间窗: At the time of recruitment
Pulsed wave TDI velocities
时间窗: At the time of recruitment
次要结局
- Pulmonary venous doppler(LV volume index)
研究者
Rashmi K S
Manipal college of health professions