Effect of Melatonin in treatment of Pediatric Status Epilepticus

Phase 2

Recruiting

• Conditions: Pediatric status epilepticus.; Other generalized epilepsy and epileptic syndromes, intractable, with status epilepticus; G40.411

• Registration Number: IRCT20181014041338N2
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1 to 15 years old children admitted in Namazi hospital PICU diagnosed with refractory and super-refractory generalized convulsive status epilepticus

Exclusion Criteria

Dissent of patient's legal guardian regarding administration of melatonin.
Inability to use NG tube for any reason.
Occurrence of adverse drug reaction to melatonin.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cessation of generalized convulsive status epilepticus. Timepoint: Continuous 24-hour monitoring from the moment the patient enters the pediatric intensive care unit. Method of measurement: Clinical observation by PICU's attending physician and staff.