Cardiopulmonary Response to Conical Positive Expiratory Breathing During Exercise in Older People.
试验速览
- 阶段
- 不适用
- 入组人数
- 12
- 主要终点
- Change of Inspiratory capacity (IC)
研究概览
简要总结
Aim of this study is to compare cardiopulmonary response to conical-PEP breathing during exercise in older people.
详细描述
It is known that all most structures and physiological functions deteriorate with age, leading to decrease exercise performance, functional decline and gradual decrease of physical activity in aging.
The most essential change of respiratory physiology are: dilatation of alveoli, enlargement of air space, decrease gas exchange surface area, loss of supporting tissue for distal airway (senile emphysema), decrees of chest wall compliance and decrease of respiratory muscle strength. These changes leading to decrease lung elastic recoil, increase residual volume and functional capacity, and increase work of breathing at rest. In addition, such changes affect respiratory function, especially dynamic hyperinflation (DH) development which could be one of the factors relate to dyspnea during exercise in aging Positive expiratory pressure (PEP) therapy for DH treatment during exercise was reported in several studies.
It is possible that PEP breathing may improve cardiopulmonary response to exercise in older people.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 60 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Elder age between 60 to 80 years old with normal spirometry
排除标准
- •They are diagnose with cardiovascular disease and, i.e. valvular heart disease, coronary heart disease, congenital heart disease, myocardial heart disease, uncontrolled hypertension, hyperlipidemia; or, present abnormal sign of heart problems previous month, such as chest pain, arrhythmia, abnormal ECG.
- •They are impair balance from neuromuscular, musculoskeletal, or vestibular problem affecting cycling and walking.
结局指标
主要结局
Change of Inspiratory capacity (IC)
时间窗: resting, immediate post exercise test and end recovery period of 10 minutes
Participants will be measured IC with slow vital capacity maneuver following American thoracic Society (ATS) and European Respiratory Society (ERS) statement for spirometry (2005).
次要结局
- Change of peak expiratory flow rate (PEF)(Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes)
- Change of respiratory rate (RR)(Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes)
- Change of Slow vital capacity (SVC)(resting, immediate post exercise test and end recovery period of 10 minutes)
- Change of inspiratory time (Ti)(Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes)
- Change of hear rate (HR)(Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes)
- Change of inspiratory and expiratory time ratio (IE ratio)(Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes)
- Change of expiratory minute ventilation (VE)(Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes)
- Change of diastolic blood pressure (DBP)(resting, immediate post exercise test and every 2 minutes during recovery period for 10 minutes)
- Change of expiratory time (Te)(Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes)
- Change of tidal volume (VT)(Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes)
- Change of mean expiratory flow rate (MEF)(Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes)
- Change of peak expiratory pressure (PEP)(Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes)
- Change of rating perceive of breathlessness (RPB)(resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes)
- Change of leg fatigue(resting, , end exercise test and end recovery period)
- Change of systolic blood pressure (SBP)(resting, immediate post exercise test and every 2 minutes during recovery period for 10 minutes)
- Change of mean expiratory pressure (MEP)(Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes)
- Change of end tidal carbon dioxide pressure (PetCO2)(Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes)
- Change of mean arterial pressure (MAP)(resting, immediate post exercise test and every 2 minutes during recovery period for 10 minutes)
- Change of pule oxygen saturation (SpO2)(Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes)
研究者
Chatchai Phimphasak
School of Physical Therapy, Faculty of Associated Medical Sciences
Khon Kaen University