Corticosteroid in acute urticaria in emergency department
- Conditions
- Adults patients with isolated acute urticaria presenting to the emergency departmentMedDRA version: 21.1Level: LLTClassification code: 10001106Term: Acute urticaria Class: 10040785Therapeutic area: Diseases [C] - Skin and Connective Tissue Diseases [C17]
- Registration Number
- CTIS2024-515308-38-00
- Lead Sponsor
- Assistance Publique Hopitaux De Paris
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 240
Age > 18 years, Acute urticaria with angioedema without laryngeal edema, Obtain patient’s consent, Social security affiliation
Pregnancy or breastfeeding, Atopic dermatitis, Eczema, Bullous pemphigoid, Acute exanthematous pustulosis, Diabetes mellitus, Gastrointestinal ulcer, Refusal to participate, Known allergy to the study drugs or formulation ingredients, Hypersensitivity to lactose, Known Renal failure defined by creatinine clearance < 10 mL/min or cardiac failure defined by ejection fraction < 40%, Acute hives with anaphylaxis, Hypersensitivity to active substance, to cetirizine, to hydroxyzine and to pipérazine and excipients, Contre-indication to corticotherapy: o Any live vaccine o Psychotic states still uncontrolled by treatment limiting the participant's compliance with the research o Some viruses in evolution (including hepatitis, herpes, chicken pox, shingles). o Any infectious condition, Bradykinin angioedema, Angioedema without urticaria (hives), Laryngeal edema with urticaria (hives), Corticosteroid administration in the previous 5 days visiting the emergency department, Antihistamines greater than 1 tablet per day in the previous 5 days visiting the ED, Other treatment for urticaria : omalizumab, montelukast, ciclosporine A, Chronic urticaria before acute urticaria diagnosis
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
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