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Effect of V0251 in Acute Vertigo

Phase 2
Completed
Conditions
Acute Vertigo
Interventions
Drug: placebo
Registration Number
NCT01583738
Lead Sponsor
Pierre Fabre Medicament
Brief Summary

Assessment of efficacy and tolerance of a new anti-dizziness drug in acute vertigo.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
132
Inclusion Criteria
  • Men or women
  • Age 18 to 70 years
  • Acute vertigo attack due to vestibular disorder
Exclusion Criteria
  • Signs of brain, brainstem and/or cerebellar dysfunction
  • Concomitant central neurological disorder
  • Psychogenic vertigo
  • Use of ototoxic drugs causing vertigo or dizziness within the last month
  • Use of anti-dizziness medications from the onset of symptoms, except if the dosage had been stable for at least 3 months

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
V0251V0251-
Placeboplacebo-
Primary Outcome Measures
NameTimeMethod
"Vertigo Symptoms Score" (VSS) rated by patient using VAS30 min
Secondary Outcome Measures
NameTimeMethod
Number of patients with Adverse Events as a measure of safety and tolerability30 min, 2 hours and 4 hours post dose
"Concomitant and Vegetative Symptoms Score" (CVSS) rated by patients using VAS30 min, 2 hours and 4 hours post dose

Trial Locations

Locations (39)

Fakultni Nemocnice Hradec Králové

🇨🇿

Hradec Králové, Czech Republic

Regional Hospital Kladno

🇨🇿

Kladno, Czech Republic

Faculty Hospital Ostrava

🇨🇿

Ostrava, Czech Republic

Faculty Hospital Královské Vinohrady

🇨🇿

Praha, Czech Republic

Faculty Hospital Motol

🇨🇿

Praha, Czech Republic

Thomayer's Teaching Hospital

🇨🇿

Praha, Czech Republic

Strepomrauska Nemocaicni a. S.

🇨🇿

Prostejov, Czech Republic

CHI Elbeuf-Louviers-Val de Reuil

🇫🇷

Elbeuf, France

Hôpital Nord

🇫🇷

St Etienne, France

CHU de Rouen, Hopital Charles Nicolle

🇫🇷

Rouen, France

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Fakultni Nemocnice Hradec Králové
🇨🇿Hradec Králové, Czech Republic

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