Investigating the effect of phycocyanin mouthwash on gingivitis

Phase 3

Conditions: Gingivitis.
Chronic gingivitis, plaque induced
K05.10

Registration Number: IRCT20240731062605N1

Lead Sponsor: Mazandaran University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 40

Inclusion Criteria

Absence of systemic disease
The presence of gingivitis caused by local irritants such as plaque and calculus

Exclusion Criteria

People who have a known allergy to compounds containing c-Phycocyanin or pure compounds from algae, or who do not want to participate in the study, are excluded from the study.
People who have used antibiotics in the last three months
Smokers
Pregnant women
People using drugs that have a specific effect on periodontium, such as anticonvulsants (such as phenytoin, carbamazepine, barbiturate, valproic acid), calcium channel blockers (such as nefidipine, verapamil, diltiazem), immunosuppressive drugs (such as cyclosporine) ) are excluded from the study.

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Dental plaque index. Timepoint: At the beginning of the study (before using mouthwashes) and 7 and 21 days after starting to use mouthwashes. Method of measurement: Observing and recording the plaque index of each tooth according to the Loe & Silness scale table.

Secondary Outcome Measures

Name	Time	Method
Gingival index. Timepoint: At the beginning of the study (before using mouthwashes) and 7 and 21 days after starting to use mouthwashes. Method of measurement: Examination and recording of gingival index for each tooth according to Loe & Silness scale table for gingival index.;Gingival bleeding index. Timepoint: At the beginning of the study (before using mouthwashes) and 7 and 21 days after starting to use mouthwashes. Method of measurement: Examining and recording gingival bleeding for each tooth using a periodontal probe and determining BOP levels in percentage.