The use of seminal plasma in IVF
Not Applicable
Completed
- Conditions
- Infertility requiring in vitro fertilisation for its managementPregnancy and Childbirth
- Registration Number
- ISRCTN52911599
- Lead Sponsor
- Homerton Fertility Centre
- Brief Summary
2015 results presented at the RCOG/RANZCOG Congress in https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1111/1471-0528.13384 (see abstract FC3.03) (added 05/02/2020)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 186
Inclusion Criteria
1. Patients undergoing IVF or ICSI treatment at the Homerton University Hospital, London, between February 2014 and September 2014
2. Female partner aged 23-39 years and with any cause infertility
Exclusion Criteria
1. The couple having undergone a prior cycle with failed fertilization
2. The use of donor oocytes or frozen-thawed sperm
3. The presence of hepatitis B, hepatitis C, or HIV infections; leucospermia or other signs of infection
4. Men with <500 µl of SP
5. Enrollment in conflicting studies
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical pregnancy rate (CPR) is assessed via pelvic ultrasound at 7-8 weeks gestation.
- Secondary Outcome Measures
Name Time Method <br> 1. Miscarriage rate is measured by pelvic ultrasound at 7-8 weeks gestation<br> 2. Multiple pregnancy rate is assessed via pelvic ultrasound at 7-8 weeks gestation<br> 3. Live birth rate (LBR) is determined through medical record review at three months after the expected date of delivery (routinely collected for all patients undergoing fertility treatment within the unit)<br>