Evaluation of Two Enteral Nutrition Strategies in Mechanically Ventilated Patients

Not Applicable

Completed

• Conditions: -Mechanically Ventilated Patients

• Registration Number: NCT00199641
• Lead Sponsor: University Hospital, Limoges

Brief Summary

The aim of this study is to compare two strategies of early enteral nutrition in terms of efficacy and complications in mechanically ventilated patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2002-07
• Study First Submitted: 2005-09-14
• Study First Submitted QC: 2005-09-14
• Study First Posted: 2005-09-20
• Status Verified: 2008-12
• Last Update Submitted: 2008-12-02
• Last Update Posted: 2008-12-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Adult (> 18 ans)
• Mechanical ventilation for > 72 hours
• Planned enteral nutrition
• Informed consent

Exclusion Criteria

• Body Mass Index < 20 kg/m2
• Enteral nutrition non indicated (ileus, splanchnic ischemia..)
• Shock (use of catecholamines, arterial blood pressure < 90 mmHg, peripheral hypoperfusion, elevation of lactates > x 1,5 normal value)
• Contraindications for gastric tube
• Pregnancy
• Previous enrollment in the present study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Incidence of nutrition failure (diarrhea, ileus, vomiting, aspiration pneumonia, elevated residual gastric volume)

Secondary Outcome Measures

Name	Time	Method
-Measured nutrition amount when compared to theorical nutrition during ICU stay
-Measured nutrition amount when compared to theorical nutrition during the first three days
-Influence of prokinetic drugs on nutrition quality

Trial Locations

Locations (2)

Service de Réanimation; 🇫🇷 Angouleme, France

Service de réanimation Polyvalente; 🇫🇷 Limoges, France