Effects of Licorice Gargle on Postoperative Sore Throat, Hoarseness and Xerostomia due to Tracheal intubatio

Not Applicable

Completed

• Conditions: Not Applicable

• Registration Number: KCT0008337
• Lead Sponsor: Kangbuk Samsung Medical Center

Brief Summary

1) “The experimental group to which the licorice gargle was applied will have a lower postoperative sore throat score after the experimental treatment than the control group to which the sugar gargle is applied” was supported by showing a statistically significant result (x²=12.412, p=.006). 2) “The experimental group to which the licorice gargle was applied will have a lower hoarse voice score after the experimental treatment than the control group to which the sugar gargle is applied” was rejected because it was not statistically significant (x²=5.045, p=.169). 3) The experimental group to which licorice gargle was applied will have a lower xerostomia score after the experimental treatment than the control group to which licorice gargle was applied” was supported by showing a statistically significant result (x²=50.436, p= <.001).

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2021-11-24
• Last Update Posted: 2 May 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1)Subjects who understood the study purposes and signed written informed consent form.
2)Adult patients 19 years and older who underwent spinal neurosurgery under general anesthesia
3)Patients who are able to understand and answer the questionnaires and communicate (except for those with mental illness or cognitive impairment)
4)Patients under general anesthesia with endotracheal intubation for 1 hour or longer
5)ASA class I or II patients under the American Society of Anesthesiologists physical status (ASA-PS) classification system (Mayhew et al., 2019)
6)Patients without cough, sore throat, hoarseness and swelling difficulty before surgery
7)Patients who have palatal reflex returned and patients with their level of consciousness is alert (Glasgow Coma Scale [GCS] score of 15)

Exclusion Criteria

The following patients were excluded: who had POST and hoarseness; who could not gargle due to dysphagia, oral cavity wound, oral cavity illness and dental problems; who did not understand information and withdrew; and who had one or more attempts at endotracheal intubation.

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
postoperative sore throat;xerostomia

Secondary Outcome Measures

Name	Time	Method
hoarseness