Can Different Intrathecal Drugs Affect Day Case Anal Surgery Recovery Duration?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 159
- 试验地点
- 1
- 主要终点
- Sensory block resolution to S3 block
研究概览
简要总结
This study aims to compare effect of adding fentanyl or dexmetomidine on duration of motor and sensory block after spinal anesthesia with prilocaine during day case perianal surgery and whether it impact time to discharge home.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Ages 18-70
- •height <155cm or >175cm
- •Day case perianal surgery
排除标准
- •Hypersensitivity to the study drugs
- •Refusal of patients.
- •Patients with contraindications for spinal anesthesia
- •previous voiding difficulty
- •patients taking anticholinergic medications.
- •emergency cases
- •Patients with contraindications for day case sitting.
研究组 & 干预措施
The bupivacaine-fentanyl group
干预措施: Bupivacaine-fentanyl (Drug)
The prilocaine-fentanyl group
干预措施: Bupivacaine-fentanyl (Drug)
The prilocaine-dexametomidine group
干预措施: Bupivacaine-fentanyl (Drug)
结局指标
主要结局
Sensory block resolution to S3 block
时间窗: at 1 min intervals until the maximum block will be achieved and at 15 min intervals thereafter until the block resolved to S3 dermatome.
The sensory block will be measured at the midclavicular line with a pinprick test (via a 22 gauge hypodermic needle)
Home discharge
时间窗: Home discharge will be assessed as the time from the end of surgery until the patients reach a post-anesthesia discharge score
(modified Alderts score) ≥9, able to void spontaneously and the sensory block resolves to the S3 dermatome.
incidence of postoperative urinary retention (POUR)
时间窗: within 6 hours after surgery
The postoperative urinary retention (POUR) will be evaluated at hourly intervals in the PACU and ward; ultrasonic bladder scanning will be used for this purpose. If the bladder volume exceeds 500 mL and the patient has not voided spontaneously, urinary catheterization will be introduced.
次要结局
未报告次要终点
研究者
Nasser Sayed
Lecturer
Ain Shams University