Role of antibiotic line locks in the prevention of tunnelled haemodialysis catheter infection: a double-blind, randomised controlled trial

Completed

• Conditions: Haemodialysis catheter related sepsis; Infections and Infestations; Complications following infusion, transfusion and therapeutic injection

• Registration Number: ISRCTN32633497
• Lead Sponsor: Wirral Hospitals NHS Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-09-26
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

All patients requiring insertion of a tunnelled haemodialysis catheter (THDC) for haemodialysis.

Exclusion Criteria

1. Patients on prolonged courses of antibiotics (oral or parenteral) i.e. for greater than 2 weeks. (This may reduce the incidence of CRI and therefore confound the results).
2. Patients with a known allergy to vancomycin or gentamicin
3. Patients known to suffer from heparin induced thrombocytopenia
4. Patients who are pregnant or plan to become pregnant. (Vancomycin and gentamicin are potentially toxic to the fetus).
5. An inability to provide informed consent to participation in the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified