How effective are antibiotics in preventing postoperative complications in patients after tooth extraction surgery?

Not Applicable

Completed

• Conditions: Pericoronitis; Oral Health

• Registration Number: ISRCTN26679089
• Lead Sponsor: Hospital of Nanjing University of Science and Technology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2018-01-31
• Study Start: 2018-12-18
• Last Update Posted: 14 January 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Current inclusion criteria:
1. Have pericoronitis in the distal aspect of a third molar and pericoronitis-related lymphadenopathy.
2. Have indication for extraction of the third molars due to recurrent infections (at least two times) occurred at certain intervals.
3. Had tooth in the vertical position.
4. Had operculum covering 1/2–2/3 of the outer surface of the tooth.

Previous inclusion criteria:
1. Have pericoronitis in the distal aspect of the mandibular third molars and pericoronitis-related lymphadenopathy.
2. Have indication for extraction of the third molars due to recurrent infections (at least two times) occurred at certain intervals.
3. Had tooth in the vertical position.
4. Had operculum covering 1/2–2/3 of the outer surface of the tooth.

Exclusion Criteria

1. Have a systemic disease
2. Pregnant women or women having suspicion of pregnancy
3. Lactating women
4. Received bisphosphonate at any time
5. Received antibiotic or anti-inflammatory drugs within the last month

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. Pain was measured using a visual analogue score (VAS) at 7th days after tooth extraction.<br> 2. Swelling was measured as the difference between the distance (mm) between the lower earlobe and the mesomentum on the extraction side at 7th days after tooth extraction.<br> 3. Mouth opening degree was measured as the distance between upper and lower incisors at 7th days after tooth extraction.<br>

Secondary Outcome Measures

Name	Time	Method
Alveolitis event was diagnosed by a dry appearance of the exposed bone in the socket after trauma.