Evaluating a protocol of antibiotic prophylaxis to reduce bacterial contamination of the bone particles collected directly from the burs used for preparation of the dental implant site
- Conditions
- Bacterial contamination of autologous bone particles collected from dental implant site.*
- Registration Number
- IRCT2017102537002N1
- Lead Sponsor
- one
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
The study is conducted in healthy human volunteers.
a need to replace the absence of one tooth with an implant supported prosthesis, no systemic diseases or contraindications to surgical procedures, no pregnancy, no routine drug use, no history of antibiotic therapy for 6 months prior to the study, no allergy to penicillin or related drugs, absence of carious lesions and local active inflammatory conditions or chronic/aggressive periodontits, presence of alveolar ridges of class II or III of Cawood and Howell (1988).
Exclusion criteria: systemic diseases that affect jaws and periodontium; orthodontic appliance; active dental caries; chronic diseases of the oral mucosa; chronic antibiotic usage; antiplaque mouthrinse consumption; drugs consumption which affect saliva flow rate; radiotherapy history.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction of bacterial contamination. Timepoint: Following end of treatment (antibiotic prophylaxis), during implant site preparation. Method of measurement: Counts (CFU) and identification of isolated bacteria.
- Secondary Outcome Measures
Name Time Method