Efficacy of oral steroids to treat the immediate symptoms of food allergy
Not Applicable
- Conditions
- Food Allergy
- Registration Number
- JPRN-UMIN000032653
- Lead Sponsor
- Aichi Children's Health and Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 103
Inclusion Criteria
Not provided
Exclusion Criteria
Patients who have a poor physical condition, such as suffering from a cold before undergoing the oral food challenge tests. Patients who had orally taken antihistamines, leukotriene receptor antagonists, beta 2 stimulants, Th 2 cytokine inhibitors, theophylline, or oral sodium cromoglycate within 72 hours before the oral food challenge tests. Patients who received oral or intravenous steroids within 2 weeks before undergoing the oral food challenge tests. Patients that the doctor assessed as being ineligible for other reasons.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The ratio of patients who experienced a worsening the ASCA total score by 10 points or more until the end of the oral food challenge according to intention to treat analysis
- Secondary Outcome Measures
Name Time Method The ratio of patients who experienced a worsening the ASCA total score by 10 points or more until the end of the oral food challenge according to per protocol analysis. The ratio of patients who experienced a worsening the ASCA total score by 10 points or more until the end of the oral food challenge, while excluding cases where the ASCA score deteriorated by 10 points or more before the administration of any drugs. The analysis of the efficacy of steroids was stratified according to each organ symptom. The efficacy of the steroids to suppress anaphylaxis and anaphylaxy shock. The analysis of the efficacy of steroids corrected by age, sex, past history of asthma and atopic dermatitis, antigen specific-IgE titer etc.