Assessment of the effect of probiotic yogurt and regular yogurt consumption on the components, inflammatory and oxidative markers and vascular endothelial function in patients with metabolic syndrome

Vice chancellor for research, Tabriz University of Medical Sciences0 个研究点目标入组 44 人开始时间: 待定最近更新: 2018年2月22日

适应症

试验速览

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•Willingness to participate; women and men aged 20-65 years; diagnosis of the metabolic syndrome based on the presence of any 3 of the criteria defined by the Iranian National Committee of Obesity: waist circumference =95 cm in both genders; fasting serum glucose =100 mg/dl; serum triglyceride =150 mg/dl; serum HDL cholesterol <40 mg/dl in men and <50 mg/dl in women; systolic blood pressure =130 mmHg and/or diastolic blood pressure =85 mmHg. Exclusion criteria: suffering from cardiovascular disease, renal failure, diabetes and gastrointestinal diseases; receiving antibiotics; supplement of vitamin and minerals, fiber, omega-3 and probiotic supplements during the two months before the start of the study; presence of pregnancy or lactation or menopause; extreme sports more than 100 minutes per week; having the weight loss diet the three months before the study; hormone therapy; taking contraceptive drugs; alcohol intake, smoking and tobacco; history of cancer and medical treatment and drugs that affect the neuroendocrine function, metabolism or appetite; thyroid problems; gastrointestinal surgery during the past year; treatment with immunomodulatory drugs one month before the study; chronic use of laxative (more than twice a week).

发起方

Vice chancellor for research, Tabriz University of Medical Sciences