CTRI/2024/01/061165
Not yet recruiting
未知
A prospective, Single-Centre study to investigate the plaque characteristics in the culprit vessels in young Indian patients (=18 - =40 yrs) with ACS undergoing PCI by Optical Coherence Tomography imaging. - YPS40
Dr Nityanand Tripathi0 sites0 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: I248- Other forms of acute ischemic heart disease
- Sponsor
- Dr Nityanand Tripathi
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Patient is \= 18 and \= 40 years of age and going for PCI of the culprit lesion (more than 90 % diameter stenosis)
- •2\. At least \=1 de novo lesions in a native coronary segment with a visually estimated diameter stenosis between \= 40 % and \< 90%
- •3\. Patient has documented ACS (unstable angina, NSTEMI or STEMI within the previous 72 hours)
- •4\. Patient demonstrates a left ventricular ejection fraction (LVEF) of \= 40% as measured prior to enrolment
- •5\. Patient understands and agrees to comply with all specified study requirements and provides written Informed Consent to this effect
Exclusion Criteria
- •1\) Patients with a medical condition that limits the life expectancy to 1 years or less
- •2\) Patients scheduled to undergo surgery within 3 months that requires interruption of DAPT
- •3\) Women who are pregnant or planning to be pregnant
- •4\) Patients with allergy to contrast agents
- •5\) Patients with coronary artery occlusion occurring at a site where a stent has already been placed or in whom observation by OCT is considered difficult
- •6\) Patients in shock
- •7\) Patients with a history of adverse reactions to aspirin, clopidogrel, or prasugrel
- •8\) Patients who are ineligible for the study in the opinion of the investigator
- •9\) Patients in whom follow\-up at 12 months after the index procedure is considered difficult
- •10\) Patients with renal failure with a serum creatinine level of 2\.0 mg/dL or more at presentation (non\-HD patients)
Outcomes
Primary Outcomes
Not specified
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