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临床试验/NCT07148661
NCT07148661已完成不适用

A Novel Technique to Remove Iatrogenic Pulmonary Parenchymal Chest Tube (PPcT): A Retrospective Analysis From a Tertiary Care Thoracic Surgery Centre

University of Health Sciences Lahore1 个研究点 分布在 1 个国家目标入组 163 人开始时间: 2024年5月1日最近更新:

试验速览

阶段
不适用
状态
已完成
入组人数
163
试验地点
1
主要终点
Hemodynamic Instability

研究概览

简要总结

Iatrogenic Pulmonary Parenchymal chest Tube (PPcT) placement is a recognized but underreported complication of tube thoracostomy, described both in the subcontinent and worldwide. This complication occurs when the chest tube inadvertently traverses the pleural cavity and penetrates the lung parenchyma. Patients with underlying lung pathology are at increased risk of having iatrogenic pulmonary parenchymal chest tube. In this study we describe the safe and minimally invasive technique to remove the PPcT without the need of video assisted thoracic surgery (VATS) or thoracotomy.

详细描述

Patients with reduced pulmonary compliance, underlying lung consolidation, or dense pleural adhesions are particularly vulnerable because these conditions limit the normal displacement of the lung away from the chest wall, predisposing it to injury during tube placement.

Diagnosing PPcT is often challenging because the clinical presentation and radiographic findings are nonspecific, and the condition may be overlooked, particularly in patients with pre-existing pulmonary disease. Computed tomography (CT) of the chest remains the gold standard for accurate diagnosis.

At our institution, we have developed and successfully implemented a stepwise, minimally invasive technique for the safe removal of PPcT over the last 19 years (since 2006), thereby avoiding thoracotomy or other invasive procedures. Once PPcT is confirmed by CT scan-while carefully differentiating true parenchymal tube placement from tubes merely located within fissures-we adopt a three-stage removal strategy:

Initial healing phase: The tube is left in situ for approximately two weeks to allow for local fibrosis and healing around the injured parenchyma, which reduces the risk of bleeding and air leak during subsequent manipulation.

Gradual staged retraction: After this period, the tube is retracted by approximately 2 cm and secured again. In cases where the tube is tightly adherent, it is rotated 360° along its axis to release any fibrous adhesions. The patient is then observed for 24 hours, with close monitoring for hemodynamic instability, hemorrhage, or air leak, and a chest radiograph is obtained to confirm tube position.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • All Participants having PPcT diagnosed on radiological basis is included in this study.

排除标准

  • Participnts having normally placed pleural chest tubes. Participants having chest tubes placed in fissures of the lung diagnosed on CT Scan of chest.

结局指标

主要结局

Hemodynamic Instability

时间窗: 24 hours

Hemodynamic Instability after staged removal of chest tube is defined as pulse rate of greater than 120/min, systolic Blood pressure of less than 80 mm of Hg, respiratory rate of greater than 24/min, hemorrhage and persistent air leak in the chest tube. Participants were observed for these above mentioned changes after every staged retraction of chest tube and responses recorded. For the participants who develop hemodynamic instability, thoracotomy was performed and underlying cause for hemodynamic instability is addressed.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Zeeshan Sarwar

Principal Investigator

University of Health Sciences Lahore

研究点 (1)

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