Molecular Assessment of Lymph Nodes in Patients With Resected (Stage I to IIIA) Non-small Cell Lung Cancer
- Conditions
- Lung Cancer
- Registration Number
- NCT00213733
- Lead Sponsor
- University Hospital, Strasbourg, France
- Brief Summary
This is a prospective study of surgically resected samples and lymph nodes of lung cancer patients. For histopathologically positive lymph nodes from a complete resection, the investigators would like to analyse tumor tissue by allelotyping and comparing these results with those observed in the primary lung tumor to establish a cartography of molecular alteration in resected lung cancer. For non histopathologically positive lymph nodes, the investigators would like to research the presence (or not) of micrometastasis by allele-specific PCR (polymerase chain reaction).
- Detailed Description
Genetic: It is a prospective study during two years with three years for follow-up. No control group is recruited.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 150
- Patients with resectable non-small cell lung cancer (stage I to IIIA), with a complete resection of the tumor and paired lymph nodes.
- Informed consent is required.
- Another cancer
- Chemotherapy before surgical treatment
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (5)
Service de Pneumologie, H么pital Lyautey
馃嚝馃嚪Strasbourg, France
Laboratoire de Biochimie et de Biologie Mol茅culaire, H么pital de Hautepierre
馃嚝馃嚪Strasbourg, France
Service d'Anatomie Pathologique, H么pital de Hautepierre
馃嚝馃嚪Strasbourg, France
Service de Chirurgie Thoracique, H么pital Civil
馃嚝馃嚪Strasbourg, France
Service de Pneumologie, H么pital de Hautepierre
馃嚝馃嚪Strasbourg, France