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临床试验/NCT02790476
NCT02790476已完成不适用

Use of Behavioral Insights to Encourage Judicious Prescribing of Opioids

University of Southern California2 个研究点 分布在 1 个国家目标入组 851 人开始时间: 2017年1月27日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
851
试验地点
2
主要终点
Number of Opioid Prescriptions for > 90 Morphine Milligram Equivalent (MME) and ≥ 50 MME

研究概览

简要总结

In collaboration with the San Diego Medical Examiner's Office and the State of California's controlled Substance Utilization Review and Evaluation System (CURES), the investigators propose to review opioid poisonings over the past 12 months and will send letters to prescribers in California when at least one of the provider's prescription(s) was filled by a patient who died of an opioid poisoning in San Diego County. The letters will be non-judgmental and factual, explaining that a patient of the provider who was being treated with prescription narcotics died of an opioid poisoning. The letter will also encourage judicious prescribing including use of the CURES system before prescribing. The investigators will evaluate physician prescribing practices over 24 months 12 months pre- and 12 months post-letter using data from the CURES database. The investigators' hypothesis is that letters will make the risk of opioids more cognitively available and that physicians will respond by prescribing opioids more carefully. This will result in fewer deaths due to misuse and more frequent use of the CURES system.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
None

入排标准

性别
All
接受健康志愿者

入选标准

  • Prescribers in California for whom at least one of their prescription(s) was filled by a patient who died of an opioid poisoning in San Diego County

排除标准

  • Prescriber is licensed outside the State of California and does not hold a California license, but the prescription was filled in California
  • The prescriber does not have a CURES report on record
  • The prescriber has issued only one opioid prescription in the last 12 months since the time of the deceased death (and the prescription was to the deceased)
  • Prescribers with unknown Drug Enforcement Agency number

结局指标

主要结局

Number of Opioid Prescriptions for > 90 Morphine Milligram Equivalent (MME) and ≥ 50 MME

时间窗: 12 months

The hypothesis is that there will be fewer opioid prescriptions both at a dose \> 90 morphine milligram equivalent (MME) and at a dose ≥ 50 MME among prescribers receiving the letter intervention, compared to control prescribers not receiving the letter intervention.

Number of Opioid and Benzodiazepine Co-prescriptions

时间窗: 12 months

The hypothesis is that there will be fewer opioid and benzodiazepine co-prescriptions for prescribers receiving the letter intervention, compared to control prescribers not receiving the letter intervention.

Average Change Over Time in Dispensed Narcotics

时间窗: 12 months

The hypothesis is that the average change over time in dispensed narcotic represented as monthly morphine milligram equivalent (MME) dose will be larger for prescribers receiving the letter intervention, compared to the average change over time for the control prescribers not receiving the letter intervention.

次要结局

  • Frequency of CURES Use(12 months)
  • Number of "New Start" Prescriptions(12 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jason Doctor

Associate Professor

University of Southern California

研究点 (2)

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