Effects of Physical Training in Altered Environmental Conditions on Exercise Performance

Not Applicable

Recruiting

• Conditions: Heat Exposure; Hypoxia, Altitude; Cold Exposure
• Interventions: Other: exercise and environmental conditions

• Registration Number: NCT06159374
• Lead Sponsor: University School of Physical Education, Krakow, Poland

Brief Summary

The main objective of the study is to evaluate the physiological-biochemical effects of physical training under artificially altered climatic conditions (using a hypoxic thermoclimatic chamber) in particular to determine the effect of such training on exercise capacity and physiological response, including the effect of training in high-performance athletes. The study will evaluate the effects of physical training and the simultaneous application of hypoxia and heat/cold on aerobic and anaerobic capacity and the physiological response of the human body. The aim of the study is to find the most favourable environmental conditions for physical training in order to maximise physical performance.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-01-01
• Study First Submitted: 2023-11-28
• Study First Submitted QC: 2023-11-28
• Status Verified: 2023-12
• Study First Posted: 2023-12-06
• Last Update Submitted: 2023-12-06
• Last Update Posted: 2023-12-13
• Primary Completion: 2024-12-31
• Study Completion: 2025-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Male
• Target Recruitment: 128

Inclusion Criteria

absence of medical contraindications to high-intensity physical exertion. The medical examination is required (included an exercise ECG, blood tests to exclude anemia or low hemoglobin and iron concentration)

Exclusion Criteria

any training (including hypoxia training or exposure) performed in the 6 months prior to the beginning of the intervention

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
normoxia-heat	exercise and environmental conditions	training performed under normoxia (200 m above sea level) and high ambient temperature (31°C) and constant humidity (40%);
hypoxia-heat	exercise and environmental conditions	training performed under normobaric hypoxia (3,000 m above sea level) and high ambient temperature (31°C) and constant humidity (40%);
normoxia-thermoneutral	exercise and environmental conditions	Training performed under normoxia (200 m above sea level) and thermoneutral conditions (21°C) and constant humidity (40%);
hypoxia-cold	exercise and environmental conditions	training performed under normobaric hypoxia (3,000 m above sea level) and low ambient temperature (-11°C) and constant humidity (40%);
hypoxia-heat-humidity	exercise and environmental conditions	training performed under normobaric hypoxia (3,000 m above sea level) and high ambient temperature (31°C) and high humidity (70%);
normoxia-cold	exercise and environmental conditions	Training performed in normoxia (200 m above sea level) and low ambient temperature (-11°C) and constant humidity (40%).
hypoxia-thermoneutral	exercise and environmental conditions	Training performed under normobaric hypoxia (3000 m above sea level) and thermoneutral conditions (21°C) and constant humidity (40%);

Primary Outcome Measures

Name	Time	Method
Measurement of anaerobic capacity	7 days before training and 7-10 days after the training. Training will last 4 weeks.	Measurement of maximal anaerobic power (Wingate Anaerobic Test)
Measurement of aerobic capacity (endurance)	7 days before training and 7-10 days after the training. Training will last 4 weeks.	Measurement of maximal oxygen uptake and determination of ventilatory thresholds (ergospirometry)
Blood analysis	Before (10 min) and after (3 min) the first and last training. The training will last 4 weeks and will consist of 12 workouts	indicators of muscle damage, inflammatory markers (interleukins), oxidative stress, lactate concentration, tissue oxygenation, selected hormones (including erythropoietin) and enzymes, HIF (hypoxia inducible factor), selected vitamins, morphology (including reticulocytes), rheology and blood biochemistry

Trial Locations

Locations (1)

University School of Physical Education in Cracow; 🇵🇱 Kraków, Poland