Comparison of radiofrequency with ozone in improving the symptoms of knee osteoarthritis

Phase 2

Recruiting

Conditions: knee osteoarthritis.
Primary generalized (osteo)arthritis
M15.0

Registration Number: IRCT20180518039700N3

Lead Sponsor: Tabriz University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 70

Inclusion Criteria

Median knee osteoarthritis (Grade 2 or 3 based on Kellegren and Lawrence knee radiography)
Patients over 45 years old
Satisfaction of patients participating in the study
Failure to respond to conservative and physiotherapy treatments over the past 6 months

Exclusion Criteria

Severe osteoarthritis (Grade 4 candidates for joint replacement surgery)
Rheumatic disease
Received previous corticosteroids 3 months ago
Clearly visible deformity of the varus or valgus of the knee
Severe knee flexion contraction
Ankylosis
Psychological disorders
Drug dependence
Hyperthyroidism
Thrombocytopenia
Pregnancy

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Physical performance. Timepoint: At the beginning of the study, in 4th session of ozone therapy and 2nd session of radio frequency (at the end of sessions of both methods) and one month after the end of sessions. Method of measurement: WOMAC questionnaire(Western Ontario and McMaster Universities Osteoarthritis Index questionnaire).;Intensity of pain. Timepoint: At the beginning of the study, in 4th session of ozone therapy and 2nd session of radio frequency (at the end of sessions of both methods) and one month after the end of sessions. Method of measurement: VAS (Visual Analog Scale) will be measured at rest and after 6 meters of walking.;Patient satisfaction. Timepoint: At the beginning of the study, in 4th session of ozone therapy and 2nd session of radio frequency (at the end of sessions of both methods) and one month after the end of sessions. Method of measurement: Question from the patient (excellent, good, acceptable and unsatisfactory).

Secondary Outcome Measures