Enhancing Behavior and Brain Response to Visual Targets Using a Computer Game

Not Applicable

Active, not recruiting

• Conditions: Neurodevelopmental Disorders
• Interventions: Behavioral: Game

• Registration Number: NCT02118649
• Lead Sponsor: Yale University

Brief Summary

Participants will play a computer game that is controlled by their gaze patterns and designed to direct attention their attention to specific on-screen targets. Visual attention to targets will be rewarded. Both visual behavior and brain response will be recorded during game play.

It is hypothesized that that, over the course of the game, relative to baseline, participants will show (a) increased looking to targets, (b) decreased response time to targets, and (c) enhanced, more efficient neural response to visual cues. It is hypothesized that clinical variability will associate with visual attention and brain response.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-04
• Study First Submitted: 2014-04-05
• Study First Submitted QC: 2014-04-16
• Study First Posted: 2014-04-21
• Status Verified: 2024-04
• Last Update Submitted: 2024-04-23
• Last Update Posted: 2024-04-25
• Primary Completion: 2026-04
• Study Completion: 2026-04

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Able to participate in an eye-tracking experiment
• Able to participate in an EEG experiment

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Exclusion Criteria

• Sensory or physical impairment that would preclude completion of protocol
• Participants taking prescription medications that may affect cognitive processes
• Participants reporting significant head trauma or history of seizures

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Game	Game	Participants will play a video game directing their gaze to on-screen targets.

Primary Outcome Measures

Name	Time	Method
EEG brain response to targets	Measures will be recorded for the duration of their visit, an expected average of 3 hours.

Secondary Outcome Measures

Name	Time	Method
Autism Diagnostic Observation Schedule	Measures will be collected during visit, an expected average of 3 hours.
Vineland Adaptive Behavior Scales, Second Edition	Measures will be collected during visit, an expected average of 3 hours.
Visual attention to targets as measured by eye-tracking	Measures will be recorded for the duration of their visit, an expected average of 3 hours.
Social Responsiveness Scale, Second Edition	Measures will be collected during visit, an expected average of 3 hours.
Differential Abilities Scale	Measures will be collected during visit, an expected average of 3 hours.
Social Anxiety Scale for Children, Revised	Measures will be collected during visit, an expected average of 3 hours.

Trial Locations

Locations (1)

Yale Child Study Center; 🇺🇸 New Haven, Connecticut, United States