Surgical Treatment for Ischaemic Heart Failure Trial (STICH): a multicentre randomised interventional treatment trial

Duke University (USA)0 个研究点目标入组 2,800 人开始时间: 2010年7月7日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•2. Women who are not of childbearing potential
•3. Aged 18 years or above
•4. Who have a left ventricular ejection fraction (LVEF) less than 0.35 measured by cardiac magnetic resonance (CMR) ventriculogram, gated single photon emission computed tomography (SPECT) ventriculogram, echocardiography, or contrast ventriculogram within three months of trial entry
•5. Who have coronary artery disease suitable for revascularisation

•1. Failure to provide informed consent
•2. Aortic valvular heart disease clearly indicating the need for aortic valve repair or replacement
•3. Cardiogenic shock (within 72 hours of randomization) as defined by the need for intra-aortic balloon support or the requirement for intravenous inotropic support
•4. Plan for percutaneous intervention of coronary artery disease
•5. Recent acute myocardial infarction judged to be an important cause of left ventricular dysfunction
•6. History of more than one prior coronary bypass operation
•7. Non-cardiac illness with a life expectancy of less than 3 years
•8. Non-cardiac illness imposing substantial operative mortality
•9. Conditions/circumstances likely to lead to poor treatment adherence (e.g., history of poor compliance, alcohol or drug dependency, psychiatric illness, no fixed abode)
•10. Previous heart, kidney, liver, or lung transplantation
•11. Current participation in another clinical trial in which a patient is taking an investigational drug or receiving an investigational medical device
•MED Therapy Eligibility Criteria:
•12. Absence of left main coronary artery disease as defined by an intraluminal stenosis of 50% or greater
•13. Absence of Canadian Class III angina or greater (angina markedly limiting ordinary activity)

发起方

Duke University (USA)